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Cryo-EM structure of the Saccharomyces cerevisiae Rpd3L histone deacetylase complex

The Rpd3L histone deacetylase (HDAC) complex is an ancient 12-subunit complex conserved in a broad range of eukaryotes that performs localized deacetylation at or near sites of recruitment by DNA-bound factors. Here we describe the cryo-EM structure of this prototypical HDAC complex that is characte...

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Detalles Bibliográficos
Autores principales:	Patel, Avinash B., Qing, Jinkang, Tam, Kelly H., Zaman, Sara, Luiso, Maria, Radhakrishnan, Ishwar, He, Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224958/ https://www.ncbi.nlm.nih.gov/pubmed/37244892 http://dx.doi.org/10.1038/s41467-023-38687-z

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