Cargando…

Targeting protein modifications in metabolic diseases: molecular mechanisms and targeted therapies

The ever-increasing prevalence of noncommunicable diseases (NCDs) represents a major public health burden worldwide. The most common form of NCD is metabolic diseases, which affect people of all ages and usually manifest their pathobiology through life-threatening cardiovascular complications. A com...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Xiumei, Xu, Mengyun, Geng, Mengya, Chen, Shuo, Little, Peter J., Xu, Suowen, Weng, Jianping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224996/ https://www.ncbi.nlm.nih.gov/pubmed/37244925 http://dx.doi.org/10.1038/s41392-023-01439-y

Ejemplares similares

Targeting FGF21 in cardiovascular and metabolic diseases: from mechanism to medicine
por: Tan, Huiling, et al.
Publicado: (2023)

Targeting inflammation and cytokine storm in COVID-19
por: Huang, Qianwen, et al.
Publicado: (2020)

ASGR1: an emerging therapeutic target in hypercholesterolemia
por: Zhao, Wenqi, et al.
Publicado: (2023)

Hyperglycemia‐mediated oocyte TET3 insufficiency predisposes offspring to glucose intolerance
por: Wu, Xiumei, et al.
Publicado: (2022)

Comparative Proteomic Analysis of Liver Tissues and Serum in db/db Mice
por: Zhang, Yu, et al.
Publicado: (2022)

Genome-Wide Transcriptional Profiling Reveals PHACTR1 as a Novel Molecular Target of Resveratrol in Endothelial Homeostasis
por: Su, Meiming, et al.
Publicado: (2022)

Serum Metabolomic Profiling in Aging Mice Using Liquid Chromatography—Mass Spectrometry
por: Yue, Tong, et al.
Publicado: (2022)

Mechanisms of Oxidized LDL-Mediated Endothelial Dysfunction and Its Consequences for the Development of Atherosclerosis
por: Jiang, Hui, et al.
Publicado: (2022)

Resveratrol in Treating Diabetes and Its Cardiovascular Complications: A Review of Its Mechanisms of Action
por: Su, Meiming, et al.
Publicado: (2022)

Mouse models of nonalcoholic fatty liver disease (NAFLD): pathomechanisms and pharmacotherapies
por: Fang, Tingyu, et al.
Publicado: (2022)

Metformin, Macrophage Dysfunction and Atherosclerosis
por: Feng, Xiaojun, et al.
Publicado: (2021)

COVID-19 and Kawasaki disease in children
por: Xu, Suowen, et al.
Publicado: (2020)

A bibliometric study of COVID-19 research in Web of Science
por: Su, Meiming, et al.
Publicado: (2021)

Endothelial Cells as a Key Cell Type for Innate Immunity: A Focused Review on RIG-I Signaling Pathway
por: Xu, Suowen, et al.
Publicado: (2022)

Non-Mouse Models of Atherosclerosis: Approaches to Exploring the Translational Potential of New Therapies
por: Kamato, Danielle, et al.
Publicado: (2022)

Histone Modification in NSCLC: Molecular Mechanisms and Therapeutic Targets
por: Bajbouj, Khuloud, et al.
Publicado: (2021)

Regulation of cholesterol homeostasis in health and diseases: from mechanisms to targeted therapeutics
por: Duan, Yajun, et al.
Publicado: (2022)

The association of elevated serum lipocalin 2 levels with diabetic peripheral neuropathy in type 2 diabetes
por: Zhang, Xi, et al.
Publicado: (2021)

The zinc finger transcription factor, KLF2, protects against COVID-19 associated endothelial dysfunction
por: Xu, Suowen, et al.
Publicado: (2021)

Metformin in cardiovascular diabetology: a focused review of its impact on endothelial function
por: Ding, Yu, et al.
Publicado: (2021)

Ribosomal proteins and human diseases: molecular mechanisms and targeted therapy
por: Kang, Jian, et al.
Publicado: (2021)

RNA modification: mechanisms and therapeutic targets
por: Qiu, Lei, et al.
Publicado: (2023)

Epigenetic modifications and targeted therapy in pediatric acute myeloid leukemia
por: Xu, Huan, et al.
Publicado: (2022)

Function and Mechanism of Novel Histone Posttranslational Modifications in Health and Disease
por: Xu, Huiwen, et al.
Publicado: (2021)

Hepatocellular Carcinoma: Molecular Mechanisms and Targeted Therapies
por: Alqahtani, Ali, et al.
Publicado: (2019)

Curcumin Inhibits Lysophosphatidic Acid Mediated MCP-1 Expression via Blocking ROCK Signalling
por: Zhou, Ying, et al.
Publicado: (2021)

Targeted protein posttranslational modifications by chemically induced proximity for cancer therapy
por: Peng, Yunhua, et al.
Publicado: (2023)

Vascular homeostasis in atherosclerosis: A holistic overview
por: Xu, Suowen, et al.
Publicado: (2022)

Impact of sodium glucose cotransporter 2 (SGLT2) inhibitors on atherosclerosis: from pharmacology to pre-clinical and clinical therapeutics
por: Liu, Zhenghong, et al.
Publicado: (2021)

GLP-1 receptor agonists (GLP-1RAs): cardiovascular actions and therapeutic potential
por: Ma, Xiaoxuan, et al.
Publicado: (2021)

Editorial: Cancer Metabolism: Molecular Targeting and Implications for Therapy
por: Ganapathy-Kanniappan, Shanmugasundaram
Publicado: (2017)

Editorial: New insights into molecular mechanisms and targeted therapy for gastrointestinal tumors
por: Feng, Haoran, et al.
Publicado: (2023)

Endothelial Dysfunction and Cardiovascular Disease: History and Analysis of the Clinical Utility of the Relationship
por: Little, Peter J., et al.
Publicado: (2021)

Gastrointestinal Stromal Tumors: Molecular Mechanisms and Targeted Therapies
por: Downs-Kelly, Erinn, et al.
Publicado: (2011)

Molecular mechanisms of resistance to HER2-targeted therapy
por: Esteva, FJ
Publicado: (2009)

Current Molecular-Targeted Therapies in NSCLC and Their Mechanism of Resistance
por: Schrank, Zachary, et al.
Publicado: (2018)

Molecular Targets of Antihypertensive Peptides: Understanding the Mechanisms of Action Based on the Pathophysiology of Hypertension
por: Majumder, Kaustav, et al.
Publicado: (2014)

Recurrent seizure‐related GRIN1 variant: Molecular mechanism and targeted therapy
por: Xu, Yuchen, et al.
Publicado: (2021)

Integrated investigation of the clinical implications and targeted landscape for RNA methylation modifications in hepatocellular carcinoma
por: Zhang, Jianping, et al.
Publicado: (2023)

Molecular targeted therapy for the treatment of gastric cancer
por: Xu, Wenting, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_aafs11fbtcl3744cb0sg7mju34