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PFI-3 induces vasorelaxation with potency to reduce extracellular calcium influx in rat mesenteric artery

BACKGROUND: PFI-3 is a small-molecule inhibitor that targets the bromodomains (BRDs) of Brahma-related gene 1 (BRG1). This monomeric compound, which has high selectivity and potent cellular effects, has recently been developed. Although PFI-3 has been reported as a potential therapeutic agent target...

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Detalles Bibliográficos
Autores principales: Li, Jing, Liang, Xue-Qi, Cui, Yun-Feng, Fu, Yu-Yang, Ma, Zi-Yue, Cui, Ying-Tao, Dong, Xian-Hui, Huang, Hai-Jun, Tong, Ting-Ting, Zhu, Ya-Mei, Xue, Ya-Dong, Wang, Yong-Zhen, Ban, Tao, Huo, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225122/
https://www.ncbi.nlm.nih.gov/pubmed/37250720
http://dx.doi.org/10.7717/peerj.15407