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Fibroepithelial Lesion Spectrum: A Case Report Documenting a Possible Transformation to a Malignant Phyllodes Tumor

We discuss the radiological-pathological aspects of a rare case of transformation of a presumed fibroadenoma (FA) to a malignant phyllodes tumor (PT) and review the literature. Phyllodes tumors often show heterogeneous histologic features with some areas indistinguishable on core needle biopsy. A co...

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Detalles Bibliográficos
Autores principales: Felsen, Amanda, Maldjian, Catherine, Hodges, Laura, Gupta, Anjuli, Fineberg, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225156/
https://www.ncbi.nlm.nih.gov/pubmed/37252609
http://dx.doi.org/10.7759/cureus.38252
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author Felsen, Amanda
Maldjian, Catherine
Hodges, Laura
Gupta, Anjuli
Fineberg, Susan
author_facet Felsen, Amanda
Maldjian, Catherine
Hodges, Laura
Gupta, Anjuli
Fineberg, Susan
author_sort Felsen, Amanda
collection PubMed
description We discuss the radiological-pathological aspects of a rare case of transformation of a presumed fibroadenoma (FA) to a malignant phyllodes tumor (PT) and review the literature. Phyllodes tumors often show heterogeneous histologic features with some areas indistinguishable on core needle biopsy. A core biopsy is often a small representation of a larger lesion. As such, a complete excisional biopsy is often needed for a definitive pathologic diagnosis. Careful clinical and imaging correlation and follow-up are necessary, even in a benign fibroepithelial lesion (FEL).
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spelling pubmed-102251562023-05-29 Fibroepithelial Lesion Spectrum: A Case Report Documenting a Possible Transformation to a Malignant Phyllodes Tumor Felsen, Amanda Maldjian, Catherine Hodges, Laura Gupta, Anjuli Fineberg, Susan Cureus Pathology We discuss the radiological-pathological aspects of a rare case of transformation of a presumed fibroadenoma (FA) to a malignant phyllodes tumor (PT) and review the literature. Phyllodes tumors often show heterogeneous histologic features with some areas indistinguishable on core needle biopsy. A core biopsy is often a small representation of a larger lesion. As such, a complete excisional biopsy is often needed for a definitive pathologic diagnosis. Careful clinical and imaging correlation and follow-up are necessary, even in a benign fibroepithelial lesion (FEL). Cureus 2023-04-28 /pmc/articles/PMC10225156/ /pubmed/37252609 http://dx.doi.org/10.7759/cureus.38252 Text en Copyright © 2023, Felsen et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pathology
Felsen, Amanda
Maldjian, Catherine
Hodges, Laura
Gupta, Anjuli
Fineberg, Susan
Fibroepithelial Lesion Spectrum: A Case Report Documenting a Possible Transformation to a Malignant Phyllodes Tumor
title Fibroepithelial Lesion Spectrum: A Case Report Documenting a Possible Transformation to a Malignant Phyllodes Tumor
title_full Fibroepithelial Lesion Spectrum: A Case Report Documenting a Possible Transformation to a Malignant Phyllodes Tumor
title_fullStr Fibroepithelial Lesion Spectrum: A Case Report Documenting a Possible Transformation to a Malignant Phyllodes Tumor
title_full_unstemmed Fibroepithelial Lesion Spectrum: A Case Report Documenting a Possible Transformation to a Malignant Phyllodes Tumor
title_short Fibroepithelial Lesion Spectrum: A Case Report Documenting a Possible Transformation to a Malignant Phyllodes Tumor
title_sort fibroepithelial lesion spectrum: a case report documenting a possible transformation to a malignant phyllodes tumor
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225156/
https://www.ncbi.nlm.nih.gov/pubmed/37252609
http://dx.doi.org/10.7759/cureus.38252
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