Shc3 facilitates breast cancer drug resistance by interacting with ErbB2 to initiate ErbB2/COX2/MDR1 axis

Multidrug resistance (MDR) is a primary limitation of breast cancer chemotherapy. The common mechanism of MDR is various anticancer drugs can be effluxed by the cell membrane protein P‐glycoprotein (P‐gp). Here, we found that ectopic overexpression of Shc3 was detected specifically in drug‐resistant...

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Detalles Bibliográficos
Autores principales: Liu, Yun, Cao, Fang, Xia, Fantong, Li, Jie, Dong, Xiaobao, Guo, Yan, Zhang, Jun, Zhao, Qiang, Liu, Yuanyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
RESEARCH ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225176/
https://www.ncbi.nlm.nih.gov/pubmed/36880347
http://dx.doi.org/10.1002/cam4.5768

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225176/
https://www.ncbi.nlm.nih.gov/pubmed/36880347
http://dx.doi.org/10.1002/cam4.5768

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