The impact of DNMT3A variant allele frequency and two different comutations on patients with de novo cytogenetically normal acute myeloid leukemia

To refine the biological and prognostic significance of DNMT3A mutations in acute myeloid leukemia (AML), we assessed the impact of DNMT3A variant allele frequency (VAF) and its comutations in this study. Using targeted next‐generation sequencing, we analyzed 171 adult patients with de novo cytogene...

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Detalles Bibliográficos
Autores principales: Chen, Xian, Tian, Chuchu, Hao, Zhuanghui, Pan, Lingang, Hong, Minglin, Wei, Wei, Muyey, Daniel Muteb, Wang, Hongwei, Chen, Xiuhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
RESEARCH ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225240/
https://www.ncbi.nlm.nih.gov/pubmed/36912186
http://dx.doi.org/10.1002/cam4.5764

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