Combined tumor necrosis factor-α (−308 G/A) and tumor necrosis factor-β (+ 252 A/G) nucleotide polymorphisms and chronicity in Egyptian children with immune thrombocytopenia

BACKGROUND: Primary immune thrombocytopenia (ITP) is a common autoimmune disorder. Secretion of TNF-α, TNF-β and IFN-γ plays a major role in the pathogenesis of ITP. OBJECTIVE: This cross-sectional study aimed to detect TNF-α (−308 G/A) and TNF-β (+ 252 A/G) gene polymorphism in a cohort of Egyptian...

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Detalles Bibliográficos
Autores principales: El-Ghamrawy, Mona, El-Gharbawi, Nesrine, Shahin, Gehan, Abdelhady, Alaa, Sayed, Rasha, Diaa, Nehal, Bishai, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225363/
https://www.ncbi.nlm.nih.gov/pubmed/36802017
http://dx.doi.org/10.1007/s12185-023-03551-9

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