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Regulation of cleavage embryo genes upon DRP1 inhibition in mouse embryonic stem cells

Dynamic-related protein 1 (DRP1) is a key protein of mitochondrial fission. In this study, we found that inhibition of activity of DRP1 led to increased levels of cleavage embryo genes in mouse embryonic stem cells (mESCs), which might reflect a transient totipotency status derived from pluripotency...

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Detalles Bibliográficos
Autores principales:	Guo, Shi-Meng, Zhang, Yi-Ran, Ma, Bing-Xin, Zhou, Li-Quan, Yin, Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225531/ https://www.ncbi.nlm.nih.gov/pubmed/37255603 http://dx.doi.org/10.3389/fcell.2023.1191797

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