A novel cell-based screen identifies chemical entities that reverse the immune-escape phenotype of metastatic tumours

Genetic and epigenetic events have been implicated in the downregulation of the cellular antigen processing and presentation machinery (APM), which in turn, has been associated with cancer evasion of the immune system. When these essential components are lacking, cancers develop the ability to subve...

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Detalles Bibliográficos
Autores principales: Nohara, Lilian L., Ellis, Samantha L. S., Dreier, Carola, Dada, Sarah, Saranchova, Iryna, Choi, Kyong Bok, Munro, Lonna, Pfeifer, Cheryl G., Al Haddad, Eliana, Coyle, Krysta M., Morrice, Jessica R., Shim, Daniel Joo Sung, Ahn, Paul, De Voogd, Nicole, Williams, David E., Cheng, Ping, Garrovillas, Emmanuel, Andersen, Raymond J., Jefferies, Wilfred A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225555/
https://www.ncbi.nlm.nih.gov/pubmed/37256225
http://dx.doi.org/10.3389/fphar.2023.1119607

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