Chondrocyte-like cells in nucleus pulposus and articular chondrocytes have similar transcriptomic profiles and are paracrine-regulated by hedgehog from notochordal cells and subchondral bone

Objective: The nucleus pulposus (NP) comprises notochordal NP cells (NCs) and chondrocyte-like NP cells (CLCs). Although morphological similarities between CLCs and chondrocytes have been reported, interactions between CLCs and NCs remain unclear. In this study, we aimed to clarify regulatory mechan...

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Detalles Bibliográficos
Autores principales: Hagizawa, Hiroki, Koyamatsu, Saeko, Okada, Seiji, Kaito, Takashi, Tsumaki, Noriyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225674/
https://www.ncbi.nlm.nih.gov/pubmed/37255604
http://dx.doi.org/10.3389/fcell.2023.1151947

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