Olmesartan alleviates SARS-CoV-2 envelope protein induced renal fibrosis by regulating HMGB1 release and autophagic degradation of TGF-β1

Background and aims: Renal damage in severe coronavirus disease 2019 (COVID-19) is highly associated with mortality. Finding relevant therapeutic candidates that can alleviate it is crucial. Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin-receptor blockers (ARBs) have been shown to...

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Detalles Bibliográficos
Autores principales: Zhou, Shilin, Yu, Zanzhe, Chen, Zihui, Ning, Fengling, Hu, Xuetao, Wu, Tiangang, Li, Mingxue, Xin, Hong, Reilly, Svetlana, Zhang, Xuemei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225711/
https://www.ncbi.nlm.nih.gov/pubmed/37256223
http://dx.doi.org/10.3389/fphar.2023.1187818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225711/
https://www.ncbi.nlm.nih.gov/pubmed/37256223
http://dx.doi.org/10.3389/fphar.2023.1187818

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