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Investigation of the prognostic role of systemic immunoinflammatory index in patients with acute pancreatitis

BACKGROUND: The aim of this study was to examine the effect of systemic immunoinflammatory index (SII), calculated on presentation to the emergency department (ED), on the prediction of clinical outcomes of patients who were diagnosed with acute pancreatitis (AP). METHODS: This research was designed...

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Autores principales: Hökenek, Ummahan Dalkılınç, Kılıç, Mazlum, Alışkan, Halil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kare Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225833/
https://www.ncbi.nlm.nih.gov/pubmed/36880632
http://dx.doi.org/10.14744/tjtes.2023.96554
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author Hökenek, Ummahan Dalkılınç
Kılıç, Mazlum
Alışkan, Halil
author_facet Hökenek, Ummahan Dalkılınç
Kılıç, Mazlum
Alışkan, Halil
author_sort Hökenek, Ummahan Dalkılınç
collection PubMed
description BACKGROUND: The aim of this study was to examine the effect of systemic immunoinflammatory index (SII), calculated on presentation to the emergency department (ED), on the prediction of clinical outcomes of patients who were diagnosed with acute pancreatitis (AP). METHODS: This research was designed as a single-center, cross-sectional, and retrospective study. Adult patients who were diagnosed with AP in the ED between October 2021 and October 2022 in the tertiary care hospital, whose diagnostic and therapeutic procedures were complete in the data recording system, have been included in the study. RESULTS: Mean age, respiratory rate, and length of stay of the non-survivors were significantly higher than the mean of the survivors (t-test, p=0.042, p=0.001, and p=0.001, respectively). Mean SII score of the patients with fatal outcome was higher than the survivors (t-test, p=0.001). ROC analysis of the SII score to predict mortality revealed that the area under the curve was found to be 0.842 (95%CI 0.772–0.898), and the Youden index was 0.614, (p=0.001). When the cutoff value of the SII score in determining mortality is >1243, the sensitivity of the score was found to be 85.0%, specificity 76.4%, positive predictive value 37.0%, and negative predictive value 96.9%. CONCLUSION: SII score was statistically significant in estimating mortality. SII calculated on presentation to the ED can be a useful scoring system to predict the clinical outcomes of patients who were admitted to the ED and were diagnosed with AP.
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spelling pubmed-102258332023-06-02 Investigation of the prognostic role of systemic immunoinflammatory index in patients with acute pancreatitis Hökenek, Ummahan Dalkılınç Kılıç, Mazlum Alışkan, Halil Ulus Travma Acil Cerrahi Derg Original Article BACKGROUND: The aim of this study was to examine the effect of systemic immunoinflammatory index (SII), calculated on presentation to the emergency department (ED), on the prediction of clinical outcomes of patients who were diagnosed with acute pancreatitis (AP). METHODS: This research was designed as a single-center, cross-sectional, and retrospective study. Adult patients who were diagnosed with AP in the ED between October 2021 and October 2022 in the tertiary care hospital, whose diagnostic and therapeutic procedures were complete in the data recording system, have been included in the study. RESULTS: Mean age, respiratory rate, and length of stay of the non-survivors were significantly higher than the mean of the survivors (t-test, p=0.042, p=0.001, and p=0.001, respectively). Mean SII score of the patients with fatal outcome was higher than the survivors (t-test, p=0.001). ROC analysis of the SII score to predict mortality revealed that the area under the curve was found to be 0.842 (95%CI 0.772–0.898), and the Youden index was 0.614, (p=0.001). When the cutoff value of the SII score in determining mortality is >1243, the sensitivity of the score was found to be 85.0%, specificity 76.4%, positive predictive value 37.0%, and negative predictive value 96.9%. CONCLUSION: SII score was statistically significant in estimating mortality. SII calculated on presentation to the ED can be a useful scoring system to predict the clinical outcomes of patients who were admitted to the ED and were diagnosed with AP. Kare Publishing 2023-03-01 /pmc/articles/PMC10225833/ /pubmed/36880632 http://dx.doi.org/10.14744/tjtes.2023.96554 Text en Copyright © 2023 Turkish Journal of Trauma and Emergency Surgery https://creativecommons.org/licenses/by-nc/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
spellingShingle Original Article
Hökenek, Ummahan Dalkılınç
Kılıç, Mazlum
Alışkan, Halil
Investigation of the prognostic role of systemic immunoinflammatory index in patients with acute pancreatitis
title Investigation of the prognostic role of systemic immunoinflammatory index in patients with acute pancreatitis
title_full Investigation of the prognostic role of systemic immunoinflammatory index in patients with acute pancreatitis
title_fullStr Investigation of the prognostic role of systemic immunoinflammatory index in patients with acute pancreatitis
title_full_unstemmed Investigation of the prognostic role of systemic immunoinflammatory index in patients with acute pancreatitis
title_short Investigation of the prognostic role of systemic immunoinflammatory index in patients with acute pancreatitis
title_sort investigation of the prognostic role of systemic immunoinflammatory index in patients with acute pancreatitis
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225833/
https://www.ncbi.nlm.nih.gov/pubmed/36880632
http://dx.doi.org/10.14744/tjtes.2023.96554
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