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Investigation of the prognostic role of systemic immunoinflammatory index in patients with acute pancreatitis
BACKGROUND: The aim of this study was to examine the effect of systemic immunoinflammatory index (SII), calculated on presentation to the emergency department (ED), on the prediction of clinical outcomes of patients who were diagnosed with acute pancreatitis (AP). METHODS: This research was designed...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Kare Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225833/ https://www.ncbi.nlm.nih.gov/pubmed/36880632 http://dx.doi.org/10.14744/tjtes.2023.96554 |
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author | Hökenek, Ummahan Dalkılınç Kılıç, Mazlum Alışkan, Halil |
author_facet | Hökenek, Ummahan Dalkılınç Kılıç, Mazlum Alışkan, Halil |
author_sort | Hökenek, Ummahan Dalkılınç |
collection | PubMed |
description | BACKGROUND: The aim of this study was to examine the effect of systemic immunoinflammatory index (SII), calculated on presentation to the emergency department (ED), on the prediction of clinical outcomes of patients who were diagnosed with acute pancreatitis (AP). METHODS: This research was designed as a single-center, cross-sectional, and retrospective study. Adult patients who were diagnosed with AP in the ED between October 2021 and October 2022 in the tertiary care hospital, whose diagnostic and therapeutic procedures were complete in the data recording system, have been included in the study. RESULTS: Mean age, respiratory rate, and length of stay of the non-survivors were significantly higher than the mean of the survivors (t-test, p=0.042, p=0.001, and p=0.001, respectively). Mean SII score of the patients with fatal outcome was higher than the survivors (t-test, p=0.001). ROC analysis of the SII score to predict mortality revealed that the area under the curve was found to be 0.842 (95%CI 0.772–0.898), and the Youden index was 0.614, (p=0.001). When the cutoff value of the SII score in determining mortality is >1243, the sensitivity of the score was found to be 85.0%, specificity 76.4%, positive predictive value 37.0%, and negative predictive value 96.9%. CONCLUSION: SII score was statistically significant in estimating mortality. SII calculated on presentation to the ED can be a useful scoring system to predict the clinical outcomes of patients who were admitted to the ED and were diagnosed with AP. |
format | Online Article Text |
id | pubmed-10225833 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Kare Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-102258332023-06-02 Investigation of the prognostic role of systemic immunoinflammatory index in patients with acute pancreatitis Hökenek, Ummahan Dalkılınç Kılıç, Mazlum Alışkan, Halil Ulus Travma Acil Cerrahi Derg Original Article BACKGROUND: The aim of this study was to examine the effect of systemic immunoinflammatory index (SII), calculated on presentation to the emergency department (ED), on the prediction of clinical outcomes of patients who were diagnosed with acute pancreatitis (AP). METHODS: This research was designed as a single-center, cross-sectional, and retrospective study. Adult patients who were diagnosed with AP in the ED between October 2021 and October 2022 in the tertiary care hospital, whose diagnostic and therapeutic procedures were complete in the data recording system, have been included in the study. RESULTS: Mean age, respiratory rate, and length of stay of the non-survivors were significantly higher than the mean of the survivors (t-test, p=0.042, p=0.001, and p=0.001, respectively). Mean SII score of the patients with fatal outcome was higher than the survivors (t-test, p=0.001). ROC analysis of the SII score to predict mortality revealed that the area under the curve was found to be 0.842 (95%CI 0.772–0.898), and the Youden index was 0.614, (p=0.001). When the cutoff value of the SII score in determining mortality is >1243, the sensitivity of the score was found to be 85.0%, specificity 76.4%, positive predictive value 37.0%, and negative predictive value 96.9%. CONCLUSION: SII score was statistically significant in estimating mortality. SII calculated on presentation to the ED can be a useful scoring system to predict the clinical outcomes of patients who were admitted to the ED and were diagnosed with AP. Kare Publishing 2023-03-01 /pmc/articles/PMC10225833/ /pubmed/36880632 http://dx.doi.org/10.14744/tjtes.2023.96554 Text en Copyright © 2023 Turkish Journal of Trauma and Emergency Surgery https://creativecommons.org/licenses/by-nc/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License |
spellingShingle | Original Article Hökenek, Ummahan Dalkılınç Kılıç, Mazlum Alışkan, Halil Investigation of the prognostic role of systemic immunoinflammatory index in patients with acute pancreatitis |
title | Investigation of the prognostic role of systemic immunoinflammatory index in patients with acute pancreatitis |
title_full | Investigation of the prognostic role of systemic immunoinflammatory index in patients with acute pancreatitis |
title_fullStr | Investigation of the prognostic role of systemic immunoinflammatory index in patients with acute pancreatitis |
title_full_unstemmed | Investigation of the prognostic role of systemic immunoinflammatory index in patients with acute pancreatitis |
title_short | Investigation of the prognostic role of systemic immunoinflammatory index in patients with acute pancreatitis |
title_sort | investigation of the prognostic role of systemic immunoinflammatory index in patients with acute pancreatitis |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225833/ https://www.ncbi.nlm.nih.gov/pubmed/36880632 http://dx.doi.org/10.14744/tjtes.2023.96554 |
work_keys_str_mv | AT hokenekummahandalkılınc investigationoftheprognosticroleofsystemicimmunoinflammatoryindexinpatientswithacutepancreatitis AT kılıcmazlum investigationoftheprognosticroleofsystemicimmunoinflammatoryindexinpatientswithacutepancreatitis AT alıskanhalil investigationoftheprognosticroleofsystemicimmunoinflammatoryindexinpatientswithacutepancreatitis |