A randomized, placebo-controlled, double-blinded mechanistic clinical trial using endotoxin to evaluate the relationship between insomnia, inflammation, and affective disturbance on pain in older adults: A protocol for the sleep and Healthy Aging Research for pain (SHARE-P) study

Chronic pain is prevalent in older adults. Treatment, especially with opioids, is often ineffective and poses considerable negative consequences in this population. To improve treatment, it is important to understand why older adults are at a heightened risk for developing chronic pain. Insomnia is...

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Detalles Bibliográficos
Autores principales: DuPont, Caitlin M., Olmstead, Richard, Reid, Matthew J., Hamilton, Katrina R., Campbell, Claudia M., Finan, Patrick H., Sadeghi, Nina, Castillo, Daisy, Irwin, Michael R., Smith, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225887/
https://www.ncbi.nlm.nih.gov/pubmed/37256193
http://dx.doi.org/10.1016/j.bbih.2023.100642

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