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Structural connectivity mediates the relationship between blood oxygenation and cognitive function in sickle cell anemia

In sickle cell disease, the relative importance of reduced hemoglobin (Hb) and peripheral oxygen saturation on brain structure remains uncertain. We applied graph-theoretical analysis to diffusion magnetic resonance imaging data to investigate the effect of structural brain connectivity on cognitive...

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Detalles Bibliográficos
Autores principales: Clayden, Jonathan D., Stotesbury, Hanne, Kawadler, Jamie M., Slee, April, Kӧlbel, Melanie, Saunders, Dawn E., Hood, Anna M., Wilkey, Olu, Layton, Mark, Inusa, Baba, Pelidis, Maria, Chakravorty, Subarna, Rees, David C., Howard, Jo, Awogbade, Moji, Liossi, Christina, Kirkham, Fenella J., Clark, Chris A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225890/
https://www.ncbi.nlm.nih.gov/pubmed/35947137
http://dx.doi.org/10.1182/bloodadvances.2021006751