Hypothalamic JNK1-hepatic fatty acid synthase axis mediates a metabolic rewiring that prevents hepatic steatosis in male mice treated with olanzapine via intraperitoneal: Additional effects of PTP1B inhibition

Olanzapine (OLA), a widely used second-generation antipsychotic (SGA), causes weight gain and metabolic alterations when administered orally to patients. Recently, we demonstrated that, contrarily to the oral treatment which induces weight gain, OLA administered via intraperitoneal (i.p.) in male mi...

Descripción completa

Detalles Bibliográficos
Autores principales: Ferreira, Vitor, Folgueira, Cintia, García-Altares, María, Guillén, Maria, Ruíz-Rosario, Mónica, DiNunzio, Giada, Garcia-Martinez, Irma, Alen, Rosa, Bookmeyer, Christoph, Jones, John G., Cigudosa, Juan C., López-Larrubia, Pilar, Correig-Blanchar, Xavier, Davis, Roger J., Sabio, Guadalupe, Rada, Patricia, Valverde, Ángela M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225935/
https://www.ncbi.nlm.nih.gov/pubmed/37230004
http://dx.doi.org/10.1016/j.redox.2023.102741

Ejemplares similares

Ejemplares similares