Progressive Memory Decline in a Patient With Atrial Septal Defect: Case Report and Literature Review

Atrial septal defect (ASD) is a common congenital anomaly that increases the risk of heart failure as well as strokes which can lead to cognitive impairment. The risk of stroke is higher when pulmonary hypertension develops and there is reversal of shunt. Stroke in ASD may be due to paradoxical embo...

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Detalles Bibliográficos
Autores principales: Wiafe, Yaw Amo, Amponsah, Gordon Manu, Asafu Adjaye Frimpong, George, Owusu, Isaac Kofi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225960/
https://www.ncbi.nlm.nih.gov/pubmed/37255701
http://dx.doi.org/10.1177/11795476231176713
Descripción
Sumario:Atrial septal defect (ASD) is a common congenital anomaly that increases the risk of heart failure as well as strokes which can lead to cognitive impairment. The risk of stroke is higher when pulmonary hypertension develops and there is reversal of shunt. Stroke in ASD may be due to paradoxical emboli from the right heart or a left ventricular thrombus which develops as a result of atrial fibrillation, a common arrhythmia in ASD. We present a case of a 32-year-old Ghanaian man with history of ASD who presented with progressive memory loss with magnetic resonance imaging scan of the brain showing multiple infarcts, microvascular disease, and cerebral atrophy.

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