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Regional disparities of prostate cancer mortality in Ecuador: an examination of trends and correlates from 2004 to 2019

BACKGROUND: Prostate cancer is the leading cause of cancer death in Ecuadorian men. However, there is a lack of information regarding the evolution of prostate cancer mortality rates in Ecuador and its regions in the last few decades. OBJECTIVE: The aim of this study was to report prostate cancer mo...

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Autores principales: Simbaña-Rivera, Katherine, Torres-Roman, J. Smith, Challapa-Mamani, Mabel R., Guerrero, Jhon, De la Cruz-Ku, Gabriel, Ybaseta-Medina, Jorge, Martinez-Herrera, José F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226193/
https://www.ncbi.nlm.nih.gov/pubmed/37248460
http://dx.doi.org/10.1186/s12889-023-15941-z
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author Simbaña-Rivera, Katherine
Torres-Roman, J. Smith
Challapa-Mamani, Mabel R.
Guerrero, Jhon
De la Cruz-Ku, Gabriel
Ybaseta-Medina, Jorge
Martinez-Herrera, José F.
author_facet Simbaña-Rivera, Katherine
Torres-Roman, J. Smith
Challapa-Mamani, Mabel R.
Guerrero, Jhon
De la Cruz-Ku, Gabriel
Ybaseta-Medina, Jorge
Martinez-Herrera, José F.
author_sort Simbaña-Rivera, Katherine
collection PubMed
description BACKGROUND: Prostate cancer is the leading cause of cancer death in Ecuadorian men. However, there is a lack of information regarding the evolution of prostate cancer mortality rates in Ecuador and its regions in the last few decades. OBJECTIVE: The aim of this study was to report prostate cancer mortality rates in Ecuador and its geographical areas and observe the evolution of these rates between 2004 and 2019. METHODS: An observational ecological study was conducted, analysing data for prostate cancer deaths from 2004 to 2019 in Ecuador. Age standardized mortality rates (ASMR) were calculated per 100,000 men using the world standard population with the direct method proposed by SEGI. Joinpoint regression analysis was performed to examine mortality trends. We used a Cluster Map to explore relationships among regions between 2015 and 2019. RESULTS: Ecuador reported 13,419 deaths by prostate cancer between 2004 and 2019, with the Coastal region accounting for 49.8% of the total deaths. The mean age at death was 79 years (± 10 years), 91.7% were elderly (more than 65 years old) and had primary education (53%). Deaths by prostate cancer were more frequently reported among mestizos (81.4%). There were no significant variations in these percentages in Ecuador and its regions during the study period. Carchi province had the highest mortality rate in 2005 and 2019 (> 13 deaths per 100,000). Heterogeneity in the evolution of mortality rates was reported among the provinces of Ecuador. Azuay decreased in the first few years, and then increased from 2010 to 2019, whereas Guayas and Pichincha decreased throughout the whole period. CONCLUSION: Although prostate cancer mortality rates in Ecuador have remained stable over the past few decades, there are significant disparities among the different regions. These findings suggest the need for the development of national and provincial registration measures, integrated healthcare actions, and targeted interventions to reduce the burden of prostate cancer in the Ecuadorian population.
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spelling pubmed-102261932023-05-30 Regional disparities of prostate cancer mortality in Ecuador: an examination of trends and correlates from 2004 to 2019 Simbaña-Rivera, Katherine Torres-Roman, J. Smith Challapa-Mamani, Mabel R. Guerrero, Jhon De la Cruz-Ku, Gabriel Ybaseta-Medina, Jorge Martinez-Herrera, José F. BMC Public Health Research BACKGROUND: Prostate cancer is the leading cause of cancer death in Ecuadorian men. However, there is a lack of information regarding the evolution of prostate cancer mortality rates in Ecuador and its regions in the last few decades. OBJECTIVE: The aim of this study was to report prostate cancer mortality rates in Ecuador and its geographical areas and observe the evolution of these rates between 2004 and 2019. METHODS: An observational ecological study was conducted, analysing data for prostate cancer deaths from 2004 to 2019 in Ecuador. Age standardized mortality rates (ASMR) were calculated per 100,000 men using the world standard population with the direct method proposed by SEGI. Joinpoint regression analysis was performed to examine mortality trends. We used a Cluster Map to explore relationships among regions between 2015 and 2019. RESULTS: Ecuador reported 13,419 deaths by prostate cancer between 2004 and 2019, with the Coastal region accounting for 49.8% of the total deaths. The mean age at death was 79 years (± 10 years), 91.7% were elderly (more than 65 years old) and had primary education (53%). Deaths by prostate cancer were more frequently reported among mestizos (81.4%). There were no significant variations in these percentages in Ecuador and its regions during the study period. Carchi province had the highest mortality rate in 2005 and 2019 (> 13 deaths per 100,000). Heterogeneity in the evolution of mortality rates was reported among the provinces of Ecuador. Azuay decreased in the first few years, and then increased from 2010 to 2019, whereas Guayas and Pichincha decreased throughout the whole period. CONCLUSION: Although prostate cancer mortality rates in Ecuador have remained stable over the past few decades, there are significant disparities among the different regions. These findings suggest the need for the development of national and provincial registration measures, integrated healthcare actions, and targeted interventions to reduce the burden of prostate cancer in the Ecuadorian population. BioMed Central 2023-05-29 /pmc/articles/PMC10226193/ /pubmed/37248460 http://dx.doi.org/10.1186/s12889-023-15941-z Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Simbaña-Rivera, Katherine
Torres-Roman, J. Smith
Challapa-Mamani, Mabel R.
Guerrero, Jhon
De la Cruz-Ku, Gabriel
Ybaseta-Medina, Jorge
Martinez-Herrera, José F.
Regional disparities of prostate cancer mortality in Ecuador: an examination of trends and correlates from 2004 to 2019
title Regional disparities of prostate cancer mortality in Ecuador: an examination of trends and correlates from 2004 to 2019
title_full Regional disparities of prostate cancer mortality in Ecuador: an examination of trends and correlates from 2004 to 2019
title_fullStr Regional disparities of prostate cancer mortality in Ecuador: an examination of trends and correlates from 2004 to 2019
title_full_unstemmed Regional disparities of prostate cancer mortality in Ecuador: an examination of trends and correlates from 2004 to 2019
title_short Regional disparities of prostate cancer mortality in Ecuador: an examination of trends and correlates from 2004 to 2019
title_sort regional disparities of prostate cancer mortality in ecuador: an examination of trends and correlates from 2004 to 2019
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226193/
https://www.ncbi.nlm.nih.gov/pubmed/37248460
http://dx.doi.org/10.1186/s12889-023-15941-z
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