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Data driven model discovery and interpretation for CAR T-cell killing using sparse identification and latent variables

In the development of cell-based cancer therapies, quantitative mathematical models of cellular interactions are instrumental in understanding treatment efficacy. Efforts to validate and interpret mathematical models of cancer cell growth and death hinge first on proposing a precise mathematical mod...

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Detalles Bibliográficos
Autores principales: Brummer, Alexander B., Xella, Agata, Woodall, Ryan, Adhikarla, Vikram, Cho, Heyrim, Gutova, Margarita, Brown, Christine E., Rockne, Russell C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226275/
https://www.ncbi.nlm.nih.gov/pubmed/37256133
http://dx.doi.org/10.3389/fimmu.2023.1115536