To increase body height and muscle strength – one medicine for two diseases? Case report of a boy with Silver-Russell syndrome and Duchenne muscular dystrophy

The coexistence of 2 genetic diseases can mutually modify their course. We describe the case of a 10-year-old boy with Sliver-Russell syndrome (SRS) and Duchenne muscular dystrophy (DMD). The patient's short stature, which is part of the clinical picture of both diseases, has been additionally...

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Autores principales: Chrzanowska, Joanna A., Bubula, Lidia, Noczyńska, Anna, Zubkiewicz-Kucharska, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2021
Materias:
Case report | Opis przypadku
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226341/
https://www.ncbi.nlm.nih.gov/pubmed/34928109
http://dx.doi.org/10.5114/pedm.2021.107724
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author Chrzanowska, Joanna A.
Bubula, Lidia
Noczyńska, Anna
Zubkiewicz-Kucharska, Agnieszka
author_facet Chrzanowska, Joanna A.
Bubula, Lidia
Noczyńska, Anna
Zubkiewicz-Kucharska, Agnieszka
author_sort Chrzanowska, Joanna A.
collection PubMed
description The coexistence of 2 genetic diseases can mutually modify their course. We describe the case of a 10-year-old boy with Sliver-Russell syndrome (SRS) and Duchenne muscular dystrophy (DMD). The patient's short stature, which is part of the clinical picture of both diseases, has been additionally aggravated by the steroid therapy, which is necessary to delay the progression of DMD. From the age of 9 years, the patient was treated with recombinant human growth hormone (rhGH) for 18 months. The following study discusses whether rhGH therapy in a child with SRS and DMD may alleviate or worsen the course of DMD, and how it affects carbohydrate metabolism disorders.
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spelling pubmed-102263412023-06-05 To increase body height and muscle strength – one medicine for two diseases? Case report of a boy with Silver-Russell syndrome and Duchenne muscular dystrophy Chrzanowska, Joanna A. Bubula, Lidia Noczyńska, Anna Zubkiewicz-Kucharska, Agnieszka Pediatr Endocrinol Diabetes Metab Case report | Opis przypadku The coexistence of 2 genetic diseases can mutually modify their course. We describe the case of a 10-year-old boy with Sliver-Russell syndrome (SRS) and Duchenne muscular dystrophy (DMD). The patient's short stature, which is part of the clinical picture of both diseases, has been additionally aggravated by the steroid therapy, which is necessary to delay the progression of DMD. From the age of 9 years, the patient was treated with recombinant human growth hormone (rhGH) for 18 months. The following study discusses whether rhGH therapy in a child with SRS and DMD may alleviate or worsen the course of DMD, and how it affects carbohydrate metabolism disorders. Termedia Publishing House 2021-12-14 2021-12 /pmc/articles/PMC10226341/ /pubmed/34928109 http://dx.doi.org/10.5114/pedm.2021.107724 Text en Copyright © Polish Society of Pediatric Endocrinology and Diabetes https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs (CC BY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) ), allowing third parties to download and share its works but not commercially purposes or to create derivative works.
spellingShingle Case report | Opis przypadku
Chrzanowska, Joanna A.
Bubula, Lidia
Noczyńska, Anna
Zubkiewicz-Kucharska, Agnieszka
To increase body height and muscle strength – one medicine for two diseases? Case report of a boy with Silver-Russell syndrome and Duchenne muscular dystrophy
title To increase body height and muscle strength – one medicine for two diseases? Case report of a boy with Silver-Russell syndrome and Duchenne muscular dystrophy
title_full To increase body height and muscle strength – one medicine for two diseases? Case report of a boy with Silver-Russell syndrome and Duchenne muscular dystrophy
title_fullStr To increase body height and muscle strength – one medicine for two diseases? Case report of a boy with Silver-Russell syndrome and Duchenne muscular dystrophy
title_full_unstemmed To increase body height and muscle strength – one medicine for two diseases? Case report of a boy with Silver-Russell syndrome and Duchenne muscular dystrophy
title_short To increase body height and muscle strength – one medicine for two diseases? Case report of a boy with Silver-Russell syndrome and Duchenne muscular dystrophy
title_sort to increase body height and muscle strength – one medicine for two diseases? case report of a boy with silver-russell syndrome and duchenne muscular dystrophy
topic Case report | Opis przypadku
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226341/
https://www.ncbi.nlm.nih.gov/pubmed/34928109
http://dx.doi.org/10.5114/pedm.2021.107724
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