Oral Dyskinesia in a Pediatric Patient Following Concurrent Use of Neuroleptics and Stimulants: Treatment Strategy Considerations to Avert Avoidable Adverse Side Effects

Withdrawal-emergent dyskinesia is a movement disorder that emerges following sudden discontinuation or rapid taper of antipsychotic medication. It is infrequently identified and typically resolves within a few weeks from symptom onset. This case report describes a unique case of reversible oral dyskinesia in a 13-year-old male in the context of concurrent neuroleptic withdrawal and stimulant titration. The extant literature describing tardive dyskinesia is well-established; however, few studies have thoroughly examined withdrawal-emergent dyskinesia and other tardive syndromes. This report highlights the importance of clinician awareness as far as the potential for extrapyramidal symptoms and withdrawal-emergent adverse effects in concomitant management of antipsychotics and stimulants in the child and adolescent populations and may help inform future treatment and management of disorders that would indicate the concurrent use of these psychotropics.