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Rising Incidence of Post Covid Rhinocerebral Mucormycosis: An Otolaryngologists Prospective

Mucormycosis or grimmer popular name, “black fungus” has evolved public concern in context of covid-19 pandemic, Covid Associated Mucormycosis (CAM) seen in Covid-19 pandemic and as a post covid sequelae. The present study was conducted to find out the incidence of the Mucormycosis, and to study its...

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Autores principales: Sahni, Dimple, Singh, Parvinder, kaur, Rajwant, Aggarwal, Sangeeta, kaur, Amandeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer India 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226435/
https://www.ncbi.nlm.nih.gov/pubmed/37362131
http://dx.doi.org/10.1007/s12070-023-03886-z
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author Sahni, Dimple
Singh, Parvinder
kaur, Rajwant
Aggarwal, Sangeeta
kaur, Amandeep
author_facet Sahni, Dimple
Singh, Parvinder
kaur, Rajwant
Aggarwal, Sangeeta
kaur, Amandeep
author_sort Sahni, Dimple
collection PubMed
description Mucormycosis or grimmer popular name, “black fungus” has evolved public concern in context of covid-19 pandemic, Covid Associated Mucormycosis (CAM) seen in Covid-19 pandemic and as a post covid sequelae. The present study was conducted to find out the incidence of the Mucormycosis, and to study its association with post-covid status and co-morbidities. A retrospective study conducted at tertiary care centre over a period of four months, involving all patients with mucormycosis of the paranasal sinuses suffering from or having a history of coronavirus disease. 59 patients had CAM, 47 patients had rhino-orbital Mucormycosis, followed by nasal and paranasal Mucormycosis in 8 patients, 3 patients with rhino-orbital-cerebral Mucormycosis, and one patient with pulmonary Mucormycosis. Diabetes mellitus was present in all 59 patients, 60.41% who had HbA1c > 10 (range 7–15), and 39.58% had HbA1c < 10 with range 6–13. Only 8.33% had controlled diabetes status, uncontroled hypertension and diabetes was seen in 34.02%. All patients were started with IV amphotericin B anti-fungal drug, and followed by oral posaconazole. Depending upon the extent of the disease surgical debridement was done in 52 patients. All patients had history of steroid intake. 7 mortality was there. Uncontrolled diabetes, over-zealous use of steroids, uncontrolled underlying primary disease or co-morbidities, prolonged hospitalization in intensive care unit or normal wards, and hyperventilation all these factors together aggravated the CAM. So it’s proper management based on, prompt diagnosis, reversal of predisposing condition with proper medical and aggressive surgical debridement remain the corner stone for this deadly CAM.
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spelling pubmed-102264352024-12-01 Rising Incidence of Post Covid Rhinocerebral Mucormycosis: An Otolaryngologists Prospective Sahni, Dimple Singh, Parvinder kaur, Rajwant Aggarwal, Sangeeta kaur, Amandeep Indian J Otolaryngol Head Neck Surg Original Article Mucormycosis or grimmer popular name, “black fungus” has evolved public concern in context of covid-19 pandemic, Covid Associated Mucormycosis (CAM) seen in Covid-19 pandemic and as a post covid sequelae. The present study was conducted to find out the incidence of the Mucormycosis, and to study its association with post-covid status and co-morbidities. A retrospective study conducted at tertiary care centre over a period of four months, involving all patients with mucormycosis of the paranasal sinuses suffering from or having a history of coronavirus disease. 59 patients had CAM, 47 patients had rhino-orbital Mucormycosis, followed by nasal and paranasal Mucormycosis in 8 patients, 3 patients with rhino-orbital-cerebral Mucormycosis, and one patient with pulmonary Mucormycosis. Diabetes mellitus was present in all 59 patients, 60.41% who had HbA1c > 10 (range 7–15), and 39.58% had HbA1c < 10 with range 6–13. Only 8.33% had controlled diabetes status, uncontroled hypertension and diabetes was seen in 34.02%. All patients were started with IV amphotericin B anti-fungal drug, and followed by oral posaconazole. Depending upon the extent of the disease surgical debridement was done in 52 patients. All patients had history of steroid intake. 7 mortality was there. Uncontrolled diabetes, over-zealous use of steroids, uncontrolled underlying primary disease or co-morbidities, prolonged hospitalization in intensive care unit or normal wards, and hyperventilation all these factors together aggravated the CAM. So it’s proper management based on, prompt diagnosis, reversal of predisposing condition with proper medical and aggressive surgical debridement remain the corner stone for this deadly CAM. Springer India 2023-05-29 2023-12 /pmc/articles/PMC10226435/ /pubmed/37362131 http://dx.doi.org/10.1007/s12070-023-03886-z Text en © Association of Otolaryngologists of India 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
spellingShingle Original Article
Sahni, Dimple
Singh, Parvinder
kaur, Rajwant
Aggarwal, Sangeeta
kaur, Amandeep
Rising Incidence of Post Covid Rhinocerebral Mucormycosis: An Otolaryngologists Prospective
title Rising Incidence of Post Covid Rhinocerebral Mucormycosis: An Otolaryngologists Prospective
title_full Rising Incidence of Post Covid Rhinocerebral Mucormycosis: An Otolaryngologists Prospective
title_fullStr Rising Incidence of Post Covid Rhinocerebral Mucormycosis: An Otolaryngologists Prospective
title_full_unstemmed Rising Incidence of Post Covid Rhinocerebral Mucormycosis: An Otolaryngologists Prospective
title_short Rising Incidence of Post Covid Rhinocerebral Mucormycosis: An Otolaryngologists Prospective
title_sort rising incidence of post covid rhinocerebral mucormycosis: an otolaryngologists prospective
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226435/
https://www.ncbi.nlm.nih.gov/pubmed/37362131
http://dx.doi.org/10.1007/s12070-023-03886-z
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