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A Review of the Cardiovascular Safety of Prucalopride in Patients With Chronic Idiopathic Constipation
Prokinetic agents, specifically 5-hydroxytryptamine type 4 (5-HT(4)) receptor agonists, have been shown to provide relief in chronic idiopathic constipation (CIC). The first-generation 5-HT(4) agonists were initially withdrawn from use owing to associations with serious cardiovascular (CV) events. T...
Autores principales: | Tack, Jan, Derakhchan, Katayoun, Gabriel, André, Spalding, William, Terreri, Brian, Youssef, Ashraf, Kreidieh, Bahij, Kowey, Peter R., Boules, Mena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226463/ https://www.ncbi.nlm.nih.gov/pubmed/36927957 http://dx.doi.org/10.14309/ajg.0000000000002249 |
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