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Vasectomy reversal in China during the recent decade: insights from a multicenter retrospective investigation

To date, there is little information about the demography of vasectomy reversal (VR) patients or the factors currently influencing VR effectiveness in China, especially after the universal two-child policy was released in 2015. In this research, demographic data and perioperative medical records of...

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Autores principales: Ren, Li-Juan, Xue, Rui-Zhi, Wu, Zi-Qiang, Zhi, Er-Lei, Li, Wei, Huang, Liang, Xiang, Xu-Yu, Li, Dao-Yuan, Lin, Xue-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226496/
https://www.ncbi.nlm.nih.gov/pubmed/35899920
http://dx.doi.org/10.4103/aja202244
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author Ren, Li-Juan
Xue, Rui-Zhi
Wu, Zi-Qiang
Zhi, Er-Lei
Li, Wei
Huang, Liang
Xiang, Xu-Yu
Li, Dao-Yuan
Lin, Xue-Ming
author_facet Ren, Li-Juan
Xue, Rui-Zhi
Wu, Zi-Qiang
Zhi, Er-Lei
Li, Wei
Huang, Liang
Xiang, Xu-Yu
Li, Dao-Yuan
Lin, Xue-Ming
author_sort Ren, Li-Juan
collection PubMed
description To date, there is little information about the demography of vasectomy reversal (VR) patients or the factors currently influencing VR effectiveness in China, especially after the universal two-child policy was released in 2015. In this research, demographic data and perioperative medical records of VR patients were extracted from seven major hospitals in different provinces or municipalities of China. Meanwhile, a telephone survey of the patients was conducted to collect follow-up information. Eventually, 448 VR cases from the past 13 years were included. The results were analyzed by stratified comparison to investigate factors that can influence postoperative vas deferens patency and pregnancy rate. Appropriately statistical methods were used, and all of the protocols were approved by the Ethics Committees of the institutes in this research. The results showed that the annual operation volume of VR quadrupled after the two-child policy was implemented. Nonmicrosurgery and a long duration of vasectomy were significantly associated with a lower patency rate. A follow-up survey showed that the general postoperative pregnancy rate was 27.2%. For female partners over the age of 35 years, the postoperative pregnancy rate showed a more severe decline, but only 35.5% of them had been given a fertility examination before their husbands’ VR surgery. Our work revealed that more patients in China have been demanding VR in recent years. High-quality microsurgery and a short duration of vasectomy are crucial for restoring patency by VR. Clinical andrologists should perform a preoperative fertility evaluation of the patients’ female partners.
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spelling pubmed-102264962023-05-30 Vasectomy reversal in China during the recent decade: insights from a multicenter retrospective investigation Ren, Li-Juan Xue, Rui-Zhi Wu, Zi-Qiang Zhi, Er-Lei Li, Wei Huang, Liang Xiang, Xu-Yu Li, Dao-Yuan Lin, Xue-Ming Asian J Androl Original Article To date, there is little information about the demography of vasectomy reversal (VR) patients or the factors currently influencing VR effectiveness in China, especially after the universal two-child policy was released in 2015. In this research, demographic data and perioperative medical records of VR patients were extracted from seven major hospitals in different provinces or municipalities of China. Meanwhile, a telephone survey of the patients was conducted to collect follow-up information. Eventually, 448 VR cases from the past 13 years were included. The results were analyzed by stratified comparison to investigate factors that can influence postoperative vas deferens patency and pregnancy rate. Appropriately statistical methods were used, and all of the protocols were approved by the Ethics Committees of the institutes in this research. The results showed that the annual operation volume of VR quadrupled after the two-child policy was implemented. Nonmicrosurgery and a long duration of vasectomy were significantly associated with a lower patency rate. A follow-up survey showed that the general postoperative pregnancy rate was 27.2%. For female partners over the age of 35 years, the postoperative pregnancy rate showed a more severe decline, but only 35.5% of them had been given a fertility examination before their husbands’ VR surgery. Our work revealed that more patients in China have been demanding VR in recent years. High-quality microsurgery and a short duration of vasectomy are crucial for restoring patency by VR. Clinical andrologists should perform a preoperative fertility evaluation of the patients’ female partners. Wolters Kluwer - Medknow 2022-07-26 /pmc/articles/PMC10226496/ /pubmed/35899920 http://dx.doi.org/10.4103/aja202244 Text en Copyright: © The Author(s)(2022) https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Ren, Li-Juan
Xue, Rui-Zhi
Wu, Zi-Qiang
Zhi, Er-Lei
Li, Wei
Huang, Liang
Xiang, Xu-Yu
Li, Dao-Yuan
Lin, Xue-Ming
Vasectomy reversal in China during the recent decade: insights from a multicenter retrospective investigation
title Vasectomy reversal in China during the recent decade: insights from a multicenter retrospective investigation
title_full Vasectomy reversal in China during the recent decade: insights from a multicenter retrospective investigation
title_fullStr Vasectomy reversal in China during the recent decade: insights from a multicenter retrospective investigation
title_full_unstemmed Vasectomy reversal in China during the recent decade: insights from a multicenter retrospective investigation
title_short Vasectomy reversal in China during the recent decade: insights from a multicenter retrospective investigation
title_sort vasectomy reversal in china during the recent decade: insights from a multicenter retrospective investigation
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226496/
https://www.ncbi.nlm.nih.gov/pubmed/35899920
http://dx.doi.org/10.4103/aja202244
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