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Antibodies Produced in Response to a Live-Attenuated Dengue Vaccine Are Functional in Activating the Complement System

BACKGROUND: Antibody-driven complement system (CS) activation has been associated with protection against symptomatic dengue virus (DENV) infection. Aggregation, opsonization, lysis, and phagocytosis are mechanisms triggered by antibody-antigen immunocomplexes following fixation of the component 1q...

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Detalles Bibliográficos
Autores principales:	Nascimento, Eduardo J M, Norwood, Brooke, Kpamegan, Eloi, Parker, Allan, Fernandes, Jesuina, Perez-Guzman, Erick, Tricou, Vianney, Braun, Ralph, Sharma, Mayuri, Dean, Hansi J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Major Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226660/ https://www.ncbi.nlm.nih.gov/pubmed/36461942 http://dx.doi.org/10.1093/infdis/jiac476

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