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RUNX2 promotes gastric cancer progression through the transcriptional activation of MGAT5 and MMP13

INTRODUCTION: RUNX2 is overexpressed in gastric cancer but the mechanism(s) through which it promotes tumor progression remain undefined. Here, we investigated the role of RUNX2 on gastric cancer pathogenesis at the molecular level. METHODS: The qRT-PCR and western bolt were utilized to examine the...

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Detalles Bibliográficos
Autores principales: Wang, Ying, Tan, Zhibo, Li, Xiaoyu, Zhang, Lili, Pei, Xiaojuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226684/
https://www.ncbi.nlm.nih.gov/pubmed/37256183
http://dx.doi.org/10.3389/fonc.2023.1133476