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Method development, validation, and impurity measurement of β-estradiol from radiolabeled [(131)I]β-estradiol using radio-high-performance liquid chromatography for radioligand of saturation binding assay

β-estradiol is an estrogen steroid hormone and acts as an estrogen receptor agonist. Radiolabeled β-estradiol is widely used as a radioligand for binding assays. In this present study, the synthesis of [(131)I]β-estradiol has been successfully carried out. Accordingly, the measurement of the radioch...

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Detalles Bibliográficos
Autores principales: Daruwati, Isti, Gwiharto, Abednego Kristande, Wongso, Hendris, Achmad, Tri Hanggono, Syaifudin, Mukh, Muchtaridi, Muchtaridi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226700/
https://www.ncbi.nlm.nih.gov/pubmed/37255880
http://dx.doi.org/10.4103/japtr.japtr_624_22