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Attainment of NICE blood pressure targets among older people with newly diagnosed hypertension: nationwide linked electronic health records cohort study

BACKGROUND: it is not known if clinical practice reflects guideline recommendations for the management of hypertension in older people and whether guideline adherence varies according to overall health status. AIMS: to describe the proportion of older people attaining National Institute for Health a...

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Autores principales: Todd, Oliver, Johnson, Oliver, Wilkinson, Chris, Hollinghurst, Joe, Dondo, Tatendashe B, Yadegarfar, Mohammad E, Sheppard, James P, McManus, Richard J, Gale, Chris P, Clegg, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226747/
https://www.ncbi.nlm.nih.gov/pubmed/37247403
http://dx.doi.org/10.1093/ageing/afad077
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author Todd, Oliver
Johnson, Oliver
Wilkinson, Chris
Hollinghurst, Joe
Dondo, Tatendashe B
Yadegarfar, Mohammad E
Sheppard, James P
McManus, Richard J
Gale, Chris P
Clegg, Andrew
author_facet Todd, Oliver
Johnson, Oliver
Wilkinson, Chris
Hollinghurst, Joe
Dondo, Tatendashe B
Yadegarfar, Mohammad E
Sheppard, James P
McManus, Richard J
Gale, Chris P
Clegg, Andrew
author_sort Todd, Oliver
collection PubMed
description BACKGROUND: it is not known if clinical practice reflects guideline recommendations for the management of hypertension in older people and whether guideline adherence varies according to overall health status. AIMS: to describe the proportion of older people attaining National Institute for Health and Care Excellence (NICE) guideline blood pressure targets within 1 year of hypertension diagnosis and determine predictors of target attainment. METHODS: a nationwide cohort study of Welsh primary care data from the Secure Anonymised Information Linkage databank including patients aged ≥65 years newly diagnosed with hypertension between 1st June 2011 and 1st June 2016. The primary outcome was attainment of NICE guideline blood pressure targets as measured by the latest blood pressure recording up to 1 year after diagnosis. Predictors of target attainment were investigated using logistic regression. RESULTS: there were 26,392 patients (55% women, median age 71 [IQR 68–77] years) included, of which 13,939 (52.8%) attained a target blood pressure within a median follow-up of 9 months. Success in attaining target blood pressure was associated with a history of atrial fibrillation (OR 1.26, 95% CI 1.11, 1.43), heart failure (OR 1.25, 95% CI 1.06, 1.49) and myocardial infarction (OR 1.20, 95% CI 1.10, 1.32), all compared to no history of each, respectively. Care home residence, the severity of frailty, and increasing co-morbidity were not associated with target attainment following adjustment for confounder variables. CONCLUSIONS: blood pressure remains insufficiently controlled 1 year after diagnosis in nearly half of older people with newly diagnosed hypertension, but target attainment appears unrelated to baseline frailty, multi-morbidity or care home residence.
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spelling pubmed-102267472023-05-30 Attainment of NICE blood pressure targets among older people with newly diagnosed hypertension: nationwide linked electronic health records cohort study Todd, Oliver Johnson, Oliver Wilkinson, Chris Hollinghurst, Joe Dondo, Tatendashe B Yadegarfar, Mohammad E Sheppard, James P McManus, Richard J Gale, Chris P Clegg, Andrew Age Ageing Research Paper BACKGROUND: it is not known if clinical practice reflects guideline recommendations for the management of hypertension in older people and whether guideline adherence varies according to overall health status. AIMS: to describe the proportion of older people attaining National Institute for Health and Care Excellence (NICE) guideline blood pressure targets within 1 year of hypertension diagnosis and determine predictors of target attainment. METHODS: a nationwide cohort study of Welsh primary care data from the Secure Anonymised Information Linkage databank including patients aged ≥65 years newly diagnosed with hypertension between 1st June 2011 and 1st June 2016. The primary outcome was attainment of NICE guideline blood pressure targets as measured by the latest blood pressure recording up to 1 year after diagnosis. Predictors of target attainment were investigated using logistic regression. RESULTS: there were 26,392 patients (55% women, median age 71 [IQR 68–77] years) included, of which 13,939 (52.8%) attained a target blood pressure within a median follow-up of 9 months. Success in attaining target blood pressure was associated with a history of atrial fibrillation (OR 1.26, 95% CI 1.11, 1.43), heart failure (OR 1.25, 95% CI 1.06, 1.49) and myocardial infarction (OR 1.20, 95% CI 1.10, 1.32), all compared to no history of each, respectively. Care home residence, the severity of frailty, and increasing co-morbidity were not associated with target attainment following adjustment for confounder variables. CONCLUSIONS: blood pressure remains insufficiently controlled 1 year after diagnosis in nearly half of older people with newly diagnosed hypertension, but target attainment appears unrelated to baseline frailty, multi-morbidity or care home residence. Oxford University Press 2023-05-27 /pmc/articles/PMC10226747/ /pubmed/37247403 http://dx.doi.org/10.1093/ageing/afad077 Text en © The Author(s) 2023. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For permissions, please email: journals.permissions@oup.com https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Research Paper
Todd, Oliver
Johnson, Oliver
Wilkinson, Chris
Hollinghurst, Joe
Dondo, Tatendashe B
Yadegarfar, Mohammad E
Sheppard, James P
McManus, Richard J
Gale, Chris P
Clegg, Andrew
Attainment of NICE blood pressure targets among older people with newly diagnosed hypertension: nationwide linked electronic health records cohort study
title Attainment of NICE blood pressure targets among older people with newly diagnosed hypertension: nationwide linked electronic health records cohort study
title_full Attainment of NICE blood pressure targets among older people with newly diagnosed hypertension: nationwide linked electronic health records cohort study
title_fullStr Attainment of NICE blood pressure targets among older people with newly diagnosed hypertension: nationwide linked electronic health records cohort study
title_full_unstemmed Attainment of NICE blood pressure targets among older people with newly diagnosed hypertension: nationwide linked electronic health records cohort study
title_short Attainment of NICE blood pressure targets among older people with newly diagnosed hypertension: nationwide linked electronic health records cohort study
title_sort attainment of nice blood pressure targets among older people with newly diagnosed hypertension: nationwide linked electronic health records cohort study
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226747/
https://www.ncbi.nlm.nih.gov/pubmed/37247403
http://dx.doi.org/10.1093/ageing/afad077
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