KLF11 regulates lung adenocarcinoma ferroptosis and chemosensitivity by suppressing GPX4

Ferroptosis, an iron-dependent non-apoptotic cell death, has been shown to play a vital role in tumor proliferation and chemotherapy resistance. Here, we report that KLF11 inhibits lung adenocarcinoma (LUAD) cell proliferation and promotes chemotherapy sensitivity by participating in the GPX4-relate...

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Detalles Bibliográficos
Autores principales: Zhao, Guangyin, Liang, Jiaqi, Shan, Guangyao, Gu, Jie, Xu, Fengkai, Lu, Chunlai, Ma, Teng, Bi, Guoshu, Zhan, Cheng, Ge, Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227016/
https://www.ncbi.nlm.nih.gov/pubmed/37248295
http://dx.doi.org/10.1038/s42003-023-04959-z

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