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Dax1 modulates ERα-dependent hypothalamic estrogen sensing in female mice

Coupling the release of pituitary hormones to the developmental stage of the oocyte is essential for female fertility. It requires estrogen to restrain kisspeptin (KISS1)-neuron pulsatility in the arcuate hypothalamic nucleus, while also exerting a surge-like effect on KISS1-neuron activity in the A...

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Detalles Bibliográficos
Autores principales: Ramos-Pittol, Jose M., Fernandes-Freitas, Isabel, Milona, Alexandra, Manchishi, Stephen M., Rainbow, Kara, Lam, Brian Y. H., Tadross, John A., Beucher, Anthony, Colledge, William H., Cebola, Inês, Murphy, Kevin G., Miguel-Aliaga, Irene, Yeo, Giles S. H., Dhillo, Waljit S., Owen, Bryn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227040/
https://www.ncbi.nlm.nih.gov/pubmed/37248237
http://dx.doi.org/10.1038/s41467-023-38618-y