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Dax1 modulates ERα-dependent hypothalamic estrogen sensing in female mice
Coupling the release of pituitary hormones to the developmental stage of the oocyte is essential for female fertility. It requires estrogen to restrain kisspeptin (KISS1)-neuron pulsatility in the arcuate hypothalamic nucleus, while also exerting a surge-like effect on KISS1-neuron activity in the A...
Autores principales: | Ramos-Pittol, Jose M., Fernandes-Freitas, Isabel, Milona, Alexandra, Manchishi, Stephen M., Rainbow, Kara, Lam, Brian Y. H., Tadross, John A., Beucher, Anthony, Colledge, William H., Cebola, Inês, Murphy, Kevin G., Miguel-Aliaga, Irene, Yeo, Giles S. H., Dhillo, Waljit S., Owen, Bryn M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227040/ https://www.ncbi.nlm.nih.gov/pubmed/37248237 http://dx.doi.org/10.1038/s41467-023-38618-y |
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