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New findings on the action of hypericin in hypoxic cancer cells with a focus on the modulation of side population cells

The presence of key hypoxia regulators, namely, hypoxia-inducible factor (HIF)-1α or HIF-2α, in tumors is associated with poor patient prognosis. Hypoxia massively activates several genes, including the one encoding the BCRP transporter that proffers multidrug resistance to cancer cells through the...

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Detalles Bibliográficos
Autores principales: Buľková, Viktória, Vargová, Jana, Babinčák, Marián, Jendželovský, Rastislav, Zdráhal, Zbyněk, Roudnický, Pavel, Košuth, Ján, Fedoročko, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editions Scientifiques Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227191/
https://www.ncbi.nlm.nih.gov/pubmed/37146419
http://dx.doi.org/10.1016/j.biopha.2023.114829