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New findings on the action of hypericin in hypoxic cancer cells with a focus on the modulation of side population cells
The presence of key hypoxia regulators, namely, hypoxia-inducible factor (HIF)-1α or HIF-2α, in tumors is associated with poor patient prognosis. Hypoxia massively activates several genes, including the one encoding the BCRP transporter that proffers multidrug resistance to cancer cells through the...
Autores principales: | Buľková, Viktória, Vargová, Jana, Babinčák, Marián, Jendželovský, Rastislav, Zdráhal, Zbyněk, Roudnický, Pavel, Košuth, Ján, Fedoročko, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Editions Scientifiques Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227191/ https://www.ncbi.nlm.nih.gov/pubmed/37146419 http://dx.doi.org/10.1016/j.biopha.2023.114829 |
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