A case of MDS/MPN overlap syndrome with ring sideroblasts and thrombocytosis: Tackling the quandary of thrombosis versus hemorrhage

KEY CLINICAL MESSAGE: No formal treatment guidelines for MDS/MPN‐RS‐T exist. With salient features such as anemia and thrombocytosis, management is individualized and aims to address anemia, thrombosis, and in some cases acquired von Willebrand's disease. ABSTRACT: Myelodysplastic/myeloprolifer...

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Detalles Bibliográficos
Autores principales: Cherniawsky, Hannah, Razavi, Habib Moshref
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227201/
https://www.ncbi.nlm.nih.gov/pubmed/37260615
http://dx.doi.org/10.1002/ccr3.7409
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author Cherniawsky, Hannah
Razavi, Habib Moshref
author_facet Cherniawsky, Hannah
Razavi, Habib Moshref
author_sort Cherniawsky, Hannah
collection PubMed
description KEY CLINICAL MESSAGE: No formal treatment guidelines for MDS/MPN‐RS‐T exist. With salient features such as anemia and thrombocytosis, management is individualized and aims to address anemia, thrombosis, and in some cases acquired von Willebrand's disease. ABSTRACT: Myelodysplastic/myeloproliferative overlap syndrome with ring sideroblasts and thrombocytosis (MDS/MPN‐RS‐T) is a rare myeloid neoplasm showing myelodysplastic and myeloproliferative features. With extremely raised platelets, possibility of acquired von Willebrand and risk of hemorrhage is increased. With this quandary in mind, a descriptive case and a brief discussion of available treatments ensues.
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spelling pubmed-102272012023-05-31 A case of MDS/MPN overlap syndrome with ring sideroblasts and thrombocytosis: Tackling the quandary of thrombosis versus hemorrhage Cherniawsky, Hannah Razavi, Habib Moshref Clin Case Rep Case Report KEY CLINICAL MESSAGE: No formal treatment guidelines for MDS/MPN‐RS‐T exist. With salient features such as anemia and thrombocytosis, management is individualized and aims to address anemia, thrombosis, and in some cases acquired von Willebrand's disease. ABSTRACT: Myelodysplastic/myeloproliferative overlap syndrome with ring sideroblasts and thrombocytosis (MDS/MPN‐RS‐T) is a rare myeloid neoplasm showing myelodysplastic and myeloproliferative features. With extremely raised platelets, possibility of acquired von Willebrand and risk of hemorrhage is increased. With this quandary in mind, a descriptive case and a brief discussion of available treatments ensues. John Wiley and Sons Inc. 2023-05-29 /pmc/articles/PMC10227201/ /pubmed/37260615 http://dx.doi.org/10.1002/ccr3.7409 Text en © 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Report
Cherniawsky, Hannah
Razavi, Habib Moshref
A case of MDS/MPN overlap syndrome with ring sideroblasts and thrombocytosis: Tackling the quandary of thrombosis versus hemorrhage
title A case of MDS/MPN overlap syndrome with ring sideroblasts and thrombocytosis: Tackling the quandary of thrombosis versus hemorrhage
title_full A case of MDS/MPN overlap syndrome with ring sideroblasts and thrombocytosis: Tackling the quandary of thrombosis versus hemorrhage
title_fullStr A case of MDS/MPN overlap syndrome with ring sideroblasts and thrombocytosis: Tackling the quandary of thrombosis versus hemorrhage
title_full_unstemmed A case of MDS/MPN overlap syndrome with ring sideroblasts and thrombocytosis: Tackling the quandary of thrombosis versus hemorrhage
title_short A case of MDS/MPN overlap syndrome with ring sideroblasts and thrombocytosis: Tackling the quandary of thrombosis versus hemorrhage
title_sort case of mds/mpn overlap syndrome with ring sideroblasts and thrombocytosis: tackling the quandary of thrombosis versus hemorrhage
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227201/
https://www.ncbi.nlm.nih.gov/pubmed/37260615
http://dx.doi.org/10.1002/ccr3.7409
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