Treatment With Small Molecule Inhibitors of Advanced Glycation End‐Products Formation and Advanced Glycation End‐Products‐Mediated Collagen Cross‐Linking Promotes Experimental Aortic Aneurysm Progression in Diabetic Mice

BACKGROUND: Although diabetes attenuates abdominal aortic aneurysms (AAAs), the mechanisms by which diabetes suppresses AAAs remain incompletely understood. Accumulation of advanced glycation end‐ (AGEs) reduces extracellular matrix (ECM) degradation in diabetes. Because ECM degradation is critical...

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Detalles Bibliográficos
Autores principales: Li, Yankui, Zheng, Xiaoya, Guo, Jia, Samura, Makoto, Ge, Yingbin, Zhao, Sihai, Li, Gang, Chen, Xiaofeng, Shoji, Takahiro, Ikezoe, Toru, Miyata, Masaaki, Xu, Baohui, Dalman, Ronald L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227285/
https://www.ncbi.nlm.nih.gov/pubmed/37158066
http://dx.doi.org/10.1161/JAHA.122.028081

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