Cargando…

Assessing the reporting quality of early phase dose-finding trial protocols: a methodological review

BACKGROUND: The paradigm of early phase dose-finding trials has evolved in recent years. Innovative dose-finding designs and protocols which combine phases I and II are becoming more popular in health research. However, the quality of these trial protocols is unknown due to a lack of specific report...

Descripción completa

Detalles Bibliográficos
Autores principales:	Villacampa, Guillermo, Patel, Dhrusti, Zheng, Haiyan, McAleese, Jessica, Rekowski, Jan, Solovyeva, Olga, Yin, Zhulin, Yap, Christina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227378/ https://www.ncbi.nlm.nih.gov/pubmed/37261325 http://dx.doi.org/10.1016/j.eclinm.2023.102020

Ejemplares similares

Enhancing reporting quality and impact of early phase dose-finding clinical trials: CONSORT Dose-finding Extension (CONSORT-DEFINE) guidance
por: Yap, Christina, et al.
Publicado: (2023)

Trends in patient‐reported outcome use in early phase dose‐finding oncology trials – an analysis of ClinicalTrials.gov
por: Lai‐Kwon, Julia, et al.
Publicado: (2021)

SPIRIT and CONSORT extensions for early phase dose-finding clinical trials: the DEFINE (DosE-FIndiNg Extensions) study protocol
por: Espinasse, Aude, et al.
Publicado: (2023)

Development of consensus-driven SPIRIT and CONSORT extensions for early phase dose-finding trials: the DEFINE study
por: Solovyeva, Olga, et al.
Publicado: (2023)

Implementation of adaptive dose-finding designs in two early phase haematological trials: clinical, operational, and methodological challenges
por: Yap, Christina, et al.
Publicado: (2013)

Statistical methods and data visualisation of patient-reported outcomes in early phase dose-finding oncology trials: a methodological review
por: Alger, Emily, et al.
Publicado: (2023)

No evidence of increased susceptibility to COVID-19 virus among radical lung radiotherapy patients
por: Lepiarczyk, Oskar, et al.
Publicado: (2021)

Quantitative neuropathology: an update on automated methodologies and implications for large scale cohorts
por: Walker, Lauren, et al.
Publicado: (2017)

An Assessment of Psychological Need in Emergency Medical Staff in the Northern Health and Social Care Trust Area
por: Aisling, McAleese, et al.
Publicado: (2016)

Posteriorly displaced salter halter fracture-dislocation at the sternoclavicular joint with associated thoracic outlet syndrome: A case report
por: McAleese, Timothy, et al.
Publicado: (2020)

Quality and Presence of Behaviour Change Techniques in Mobile Apps for the Mediterranean Diet: A Content Analysis of Android Google Play and Apple App Store Apps
por: McAleese, Daniel, et al.
Publicado: (2022)

Protocol of a pilot-scale, single-arm, observational study to assess the utility and acceptability of a wearable hydration monitor in haemodialysis patients
por: Sandys, Vicki, et al.
Publicado: (2022)

Does lucency equate to revision? A five-year retrospective review of Attune and Triathlon total knee arthroplasty
por: O’Donovan, Paul, et al.
Publicado: (2023)

Neuroendocrine carcinoma arising in soft tissue: three case reports and literature review
por: Hyer, Steve L, et al.
Publicado: (2007)

‘Emigration is a matter of self-preservation. The working conditions . . . are killing us slowly’: qualitative insights into health professional emigration from Ireland
por: Humphries, Niamh, et al.
Publicado: (2015)

Thyroid radiation shields: A potential source of intraoperative infection
por: McAleese, T., et al.
Publicado: (2020)

Data on elemental concentrations in marine sediments from the South and South West of England
por: Richir, Jonathan, et al.
Publicado: (2021)

Bilateral patellar tendon rupture following low-energy trauma in a young patient without predisposing risk factors
por: Murphy, Suzanne M., et al.
Publicado: (2022)

Arylamine N-acetyltransferase 1 deficiency inhibits drug-induced cell death in breast cancer cells: switch from cytochrome C-dependent apoptosis to necroptosis
por: McAleese, Courtney E., et al.
Publicado: (2022)

Existing Non-cardiac Comorbidities Negatively Impact Quality of Life Gains After Left Ventricular Assist Device Implant
por: Patel, Dhrusti, et al.
Publicado: (2020)

Gone for good? An online survey of emigrant health professionals using Facebook as a recruitment tool
por: McAleese, Sara, et al.
Publicado: (2016)

The consequences of Ireland’s culture of medical migration
por: Humphries, Niamh, et al.
Publicado: (2017)

Kocuria rhizophila prosthetic hip joint infection
por: McAleese, Timothy, et al.
Publicado: (2023)

Recurrent chondroblastoma of the talus: A case report and literature review of recurrent lesions in the foot and ankle
por: Jagiella-Lodise, Olivia, et al.
Publicado: (2023)

Non-EU migrant doctors in Ireland: applying a typology of health worker migration
por: Humphries, Niamh, et al.
Publicado: (2014)

Applying a typology of health worker migration to non-EU migrant doctors in Ireland
por: Humphries, Niamh, et al.
Publicado: (2015)

Intraosseous schwannoma of the femur in a patient with monoclonal gammopathy of undetermined significance
por: McAleese, Timothy, et al.
Publicado: (2020)

Bilateral Mechanically-Assisted Crevice Corrosion Resulting in Femoral Stem-Head Dissociation in Metal-on-Polyethylene Total Hip Arthroplasty
por: McAleese, Timothy, et al.
Publicado: (2021)

A Systematic Review of the Factors Associated with Post-Traumatic Growth in Parents Following Admission of Their Child to the Intensive Care Unit
por: O’Toole, S., et al.
Publicado: (2022)

Foot and ankle service adaptation in response to COVID-19 and beyond
por: Feeley, I., et al.
Publicado: (2020)

A cycle of brain gain, waste and drain - a qualitative study of non-EU migrant doctors in Ireland
por: Humphries, Niamh, et al.
Publicado: (2013)

Passing through – reasons why migrant doctors in Ireland plan to stay, return home or migrate onwards to new destination countries
por: Brugha, Ruairí, et al.
Publicado: (2016)

Predictors of career progression and obstacles and opportunities for non-EU hospital doctors to undertake postgraduate training in Ireland
por: Tyrrell, Ella, et al.
Publicado: (2016)

Implementation of platform trials in the COVID-19 pandemic: A rapid review
por: Vanderbeek, Alyssa M., et al.
Publicado: (2022)

A pragmatic approach to the design and calibration of a Bayesian CRM dose finding trial
por: Cole, Michael, et al.
Publicado: (2015)

Implementing the EffTox dose-finding design in the Matchpoint trial
por: Brock, Kristian, et al.
Publicado: (2017)

Dose transition pathways: a design, analysis and operational tool for dose-finding trials using model-based designs
por: Yap, Christina, et al.
Publicado: (2015)

Emerging Antibiotic Resistance Patterns in a Neonatal Intensive Care Unit in Pune, India: A 2-Year Retrospective Study
por: Shah, Mubashir Hassan, et al.
Publicado: (2022)

Re-challenge chemotherapy with gemcitabine plus carboplatin in patients with non-small cell lung cancer
por: Khan, Khurum, et al.
Publicado: (2013)

Neuropsychiatric symptoms in limbic-predominant age-related TDP-43 encephalopathy and Alzheimer’s disease
por: Liu, Kathy Y, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_m0du8qs87vp5g9sc09g35ho2ru