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MicroRNA miR-214-5p induces senescence of microvascular endothelial cells by targeting the JAG1/Notch signaling pathway

During cellular senescence, irreversible cell cycle arrest is accompanied by morphological and genetic alterations. MicroRNAs (miRNAs) play a critical role in regulating senescence by modulating the abundance of crucial senescence regulatory proteins. Therefore, to identify novel senescence-associat...

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Detalles Bibliográficos
Autores principales: Jo, Hye-ram, Hwang, Jiwon, Jeong, Jae-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227379/
https://www.ncbi.nlm.nih.gov/pubmed/37260583
http://dx.doi.org/10.1016/j.ncrna.2023.05.002