A Neuroligin-1 mutation associated with Alzheimer’s disease produces memory and age-dependent impairments in hippocampal plasticity

Alzheimer’s disease (AD) is characterized by memory impairments and age-dependent synapse loss. Experimental and clinical studies have shown decreased expression of the glutamatergic protein Neuroligin-1 (Nlgn1) in AD. However, the consequences of a sustained reduction of Nlgn1 are unknown. Here, we...

Descripción completa

Detalles Bibliográficos
Autores principales: Arias-Aragón, Francisco, Tristán-Clavijo, Enriqueta, Martínez-Gallego, Irene, Robles-Lanuza, Estefanía, Coatl-Cuaya, Heriberto, Martín-Cuevas, Celia, Sánchez-Hidalgo, Ana C., Rodríguez-Moreno, Antonio, Martinez-Mir, Amalia, Scholl, Francisco G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227424/
https://www.ncbi.nlm.nih.gov/pubmed/37260747
http://dx.doi.org/10.1016/j.isci.2023.106868

Ejemplares similares

Ejemplares similares