Transcriptome sequencing suggests that pre-mRNA splicing counteracts widespread intronic cleavage and polyadenylation

Alternative splicing (AS) and alternative polyadenylation (APA) are two crucial steps in the post-transcriptional regulation of eukaryotic gene expression. Protocols capturing and sequencing RNA 3′-ends have uncovered widespread intronic polyadenylation (IPA) in normal and disease conditions, where...

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Detalles Bibliográficos
Autores principales: Vlasenok, Maria, Margasyuk, Sergey, Pervouchine, Dmitri D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Standard Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227441/
https://www.ncbi.nlm.nih.gov/pubmed/37260513
http://dx.doi.org/10.1093/nargab/lqad051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227441/
https://www.ncbi.nlm.nih.gov/pubmed/37260513
http://dx.doi.org/10.1093/nargab/lqad051

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