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Acute health effects of heated tobacco products: comparative analysis with traditional cigarettes and electronic cigarettes in young adults

BACKGROUND: Heated tobacco products (HTPs) were designed to deliver nicotine by heating the tobacco instead of burning it. This study aimed to examine the acute health effects on the respiratory and cardiovascular systems during the use of HTPs and compare these effects with acute health effects evo...

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Autores principales: Majek, Paulina, Jankowski, Mateusz, Brożek, Grzegorz Marek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227633/
https://www.ncbi.nlm.nih.gov/pubmed/37260463
http://dx.doi.org/10.1183/23120541.00595-2022
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author Majek, Paulina
Jankowski, Mateusz
Brożek, Grzegorz Marek
author_facet Majek, Paulina
Jankowski, Mateusz
Brożek, Grzegorz Marek
author_sort Majek, Paulina
collection PubMed
description BACKGROUND: Heated tobacco products (HTPs) were designed to deliver nicotine by heating the tobacco instead of burning it. This study aimed to examine the acute health effects on the respiratory and cardiovascular systems during the use of HTPs and compare these effects with acute health effects evoked by cigarette smoking or electronic cigarettes (e-cigarettes). METHODS: The study group comprised 160 healthy young adults (age 23 years; quartile 1 (Q1) 21 years; quartile 3 (Q3) 26 years) with both sexes divided into groups according to their smoking status: 40 HTP users (H group), 40 traditional cigarette smokers (T group), 40 e-cigarette users (E group) and 40 non-smokers (C group). Heart rate, blood pressure, oxygen saturation, exhaled nitric oxide fraction (F(ENO)), carbon monoxide concentration, temperature of exhaled air and spirometry were measured three times: initially, immediately after the exposure, and after 30 min. The exposure differed depending on smoking status: heating HTP, smoking a cigarette, using an e-cigarette and simulation of smoking. RESULTS: After 5 min of exposure, a significant decrease in F(ENO) was observed in the H and E groups, from 12.8±5.5 ppb to 11.2±5.3 ppb in the H group and from 16.9±6.5 ppb to 14.2±6.8 ppb in the E group (p<0.01). A slight but statistically significant increase in the temperature of exhaled air after 30 min was observed in groups T and E, from 34.1°C (Q1 33.6°C; Q3 34.4°C) to 34.4°C (Q1 34.1°C; Q3 34.6°C) (p=0.02) in the T group and from 34.2°C (Q1 33.9°C; Q3 34.5°C) to 34.4°C (Q1 33.8°C; Q3 34.6°C) (p<0.01) in the E group. A significant increase in heart rate and blood pressure was observed in the T, E and H groups. Only cigarette smoking increased carbon monoxide levels (p<0.01). CONCLUSIONS: The use of HTPs elicits acute respiratory and cardiovascular health effects.
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spelling pubmed-102276332023-05-31 Acute health effects of heated tobacco products: comparative analysis with traditional cigarettes and electronic cigarettes in young adults Majek, Paulina Jankowski, Mateusz Brożek, Grzegorz Marek ERJ Open Res Original Research Articles BACKGROUND: Heated tobacco products (HTPs) were designed to deliver nicotine by heating the tobacco instead of burning it. This study aimed to examine the acute health effects on the respiratory and cardiovascular systems during the use of HTPs and compare these effects with acute health effects evoked by cigarette smoking or electronic cigarettes (e-cigarettes). METHODS: The study group comprised 160 healthy young adults (age 23 years; quartile 1 (Q1) 21 years; quartile 3 (Q3) 26 years) with both sexes divided into groups according to their smoking status: 40 HTP users (H group), 40 traditional cigarette smokers (T group), 40 e-cigarette users (E group) and 40 non-smokers (C group). Heart rate, blood pressure, oxygen saturation, exhaled nitric oxide fraction (F(ENO)), carbon monoxide concentration, temperature of exhaled air and spirometry were measured three times: initially, immediately after the exposure, and after 30 min. The exposure differed depending on smoking status: heating HTP, smoking a cigarette, using an e-cigarette and simulation of smoking. RESULTS: After 5 min of exposure, a significant decrease in F(ENO) was observed in the H and E groups, from 12.8±5.5 ppb to 11.2±5.3 ppb in the H group and from 16.9±6.5 ppb to 14.2±6.8 ppb in the E group (p<0.01). A slight but statistically significant increase in the temperature of exhaled air after 30 min was observed in groups T and E, from 34.1°C (Q1 33.6°C; Q3 34.4°C) to 34.4°C (Q1 34.1°C; Q3 34.6°C) (p=0.02) in the T group and from 34.2°C (Q1 33.9°C; Q3 34.5°C) to 34.4°C (Q1 33.8°C; Q3 34.6°C) (p<0.01) in the E group. A significant increase in heart rate and blood pressure was observed in the T, E and H groups. Only cigarette smoking increased carbon monoxide levels (p<0.01). CONCLUSIONS: The use of HTPs elicits acute respiratory and cardiovascular health effects. European Respiratory Society 2023-05-30 /pmc/articles/PMC10227633/ /pubmed/37260463 http://dx.doi.org/10.1183/23120541.00595-2022 Text en Copyright ©The authors 2023 https://creativecommons.org/licenses/by-nc/4.0/This version is distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0. For commercial reproduction rights and permissions contact permissions@ersnet.org (mailto:permissions@ersnet.org)
spellingShingle Original Research Articles
Majek, Paulina
Jankowski, Mateusz
Brożek, Grzegorz Marek
Acute health effects of heated tobacco products: comparative analysis with traditional cigarettes and electronic cigarettes in young adults
title Acute health effects of heated tobacco products: comparative analysis with traditional cigarettes and electronic cigarettes in young adults
title_full Acute health effects of heated tobacco products: comparative analysis with traditional cigarettes and electronic cigarettes in young adults
title_fullStr Acute health effects of heated tobacco products: comparative analysis with traditional cigarettes and electronic cigarettes in young adults
title_full_unstemmed Acute health effects of heated tobacco products: comparative analysis with traditional cigarettes and electronic cigarettes in young adults
title_short Acute health effects of heated tobacco products: comparative analysis with traditional cigarettes and electronic cigarettes in young adults
title_sort acute health effects of heated tobacco products: comparative analysis with traditional cigarettes and electronic cigarettes in young adults
topic Original Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227633/
https://www.ncbi.nlm.nih.gov/pubmed/37260463
http://dx.doi.org/10.1183/23120541.00595-2022
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