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Risk stratified monitoring for methotrexate toxicity in immune mediated inflammatory diseases: prognostic model development and validation using primary care data from the UK

OBJECTIVE: To develop and validate a prognostic model to inform risk stratified decisions on frequency of monitoring blood tests during long term methotrexate treatment. DESIGN: Retrospective cohort study. SETTING: Electronic health records within the UK’s Clinical Practice Research Datalink (CPRD)...

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Detalles Bibliográficos
Autores principales: Nakafero, Georgina, Grainge, Matthew J, Williams, Hywel C, Card, Tim, Taal, Maarten W, Aithal, Guruprasad P, Fox, Christopher P, Mallen, Christian D, van der Windt, Danielle A, Stevenson, Matthew D, Riley, Richard D, Abhishek, Abhishek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227711/
https://www.ncbi.nlm.nih.gov/pubmed/37253479
http://dx.doi.org/10.1136/bmj-2022-074678