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Fatal case of Capnocytophaga sepsis from a dog bite in a patient with splenic hypoplasia

BACKGROUND: Capnocytophaga canimorsus is an oral commensal bacteria in dogs and may cause severe infection following a dog bite. This is a case of fatal C. canimorsus sepsis with acute infectious purpura fulminans (AIPF) in a healthy patient with splenic hypoplasia. CASE PRESENTATION: A healthy 49‐y...

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Autores principales: Kondo, Natsuki, Matsumura, Yosuke, Sugiyama, Takuya, Miyahara, Masaya, Imamura, Ai, Kasahara, Yuki, Nagashima, Hideaki, Hanaoka, Noriyuki, Fujiyoshi, Naohiko, Inaba, Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227742/
https://www.ncbi.nlm.nih.gov/pubmed/37261373
http://dx.doi.org/10.1002/ams2.849
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author Kondo, Natsuki
Matsumura, Yosuke
Sugiyama, Takuya
Miyahara, Masaya
Imamura, Ai
Kasahara, Yuki
Nagashima, Hideaki
Hanaoka, Noriyuki
Fujiyoshi, Naohiko
Inaba, Shin
author_facet Kondo, Natsuki
Matsumura, Yosuke
Sugiyama, Takuya
Miyahara, Masaya
Imamura, Ai
Kasahara, Yuki
Nagashima, Hideaki
Hanaoka, Noriyuki
Fujiyoshi, Naohiko
Inaba, Shin
author_sort Kondo, Natsuki
collection PubMed
description BACKGROUND: Capnocytophaga canimorsus is an oral commensal bacteria in dogs and may cause severe infection following a dog bite. This is a case of fatal C. canimorsus sepsis with acute infectious purpura fulminans (AIPF) in a healthy patient with splenic hypoplasia. CASE PRESENTATION: A healthy 49‐year‐old man was admitted to the intensive care unit (ICU) for septic shock and AIPF 4 days after a dog bite to his mouth. Computed tomography revealed a small spleen measuring 53 cm(3) but no other source of infection. Despite intensive care, the patient died of multiple organ failure and progressive shock on the fifth ICU day. Polymerase chain reaction of blood samples identified the C. canimorsus gene on a later day. CONCLUSION: Capnocytophaga canimorsus from dog bites may cause fatal AIPF. Splenic hypoplasia and bite wounds in well‐perfused areas such as the oral cavity are possible risk factors for sepsis. All dog bites should warrant medical attention.
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spelling pubmed-102277422023-05-31 Fatal case of Capnocytophaga sepsis from a dog bite in a patient with splenic hypoplasia Kondo, Natsuki Matsumura, Yosuke Sugiyama, Takuya Miyahara, Masaya Imamura, Ai Kasahara, Yuki Nagashima, Hideaki Hanaoka, Noriyuki Fujiyoshi, Naohiko Inaba, Shin Acute Med Surg Case Report BACKGROUND: Capnocytophaga canimorsus is an oral commensal bacteria in dogs and may cause severe infection following a dog bite. This is a case of fatal C. canimorsus sepsis with acute infectious purpura fulminans (AIPF) in a healthy patient with splenic hypoplasia. CASE PRESENTATION: A healthy 49‐year‐old man was admitted to the intensive care unit (ICU) for septic shock and AIPF 4 days after a dog bite to his mouth. Computed tomography revealed a small spleen measuring 53 cm(3) but no other source of infection. Despite intensive care, the patient died of multiple organ failure and progressive shock on the fifth ICU day. Polymerase chain reaction of blood samples identified the C. canimorsus gene on a later day. CONCLUSION: Capnocytophaga canimorsus from dog bites may cause fatal AIPF. Splenic hypoplasia and bite wounds in well‐perfused areas such as the oral cavity are possible risk factors for sepsis. All dog bites should warrant medical attention. John Wiley and Sons Inc. 2023-05-30 /pmc/articles/PMC10227742/ /pubmed/37261373 http://dx.doi.org/10.1002/ams2.849 Text en © 2023 The Authors. Acute Medicine & Surgery published by John Wiley & Sons Australia, Ltd on behalf of Japanese Association for Acute Medicine. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Report
Kondo, Natsuki
Matsumura, Yosuke
Sugiyama, Takuya
Miyahara, Masaya
Imamura, Ai
Kasahara, Yuki
Nagashima, Hideaki
Hanaoka, Noriyuki
Fujiyoshi, Naohiko
Inaba, Shin
Fatal case of Capnocytophaga sepsis from a dog bite in a patient with splenic hypoplasia
title Fatal case of Capnocytophaga sepsis from a dog bite in a patient with splenic hypoplasia
title_full Fatal case of Capnocytophaga sepsis from a dog bite in a patient with splenic hypoplasia
title_fullStr Fatal case of Capnocytophaga sepsis from a dog bite in a patient with splenic hypoplasia
title_full_unstemmed Fatal case of Capnocytophaga sepsis from a dog bite in a patient with splenic hypoplasia
title_short Fatal case of Capnocytophaga sepsis from a dog bite in a patient with splenic hypoplasia
title_sort fatal case of capnocytophaga sepsis from a dog bite in a patient with splenic hypoplasia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227742/
https://www.ncbi.nlm.nih.gov/pubmed/37261373
http://dx.doi.org/10.1002/ams2.849
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