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Structural basis of human PRPS2 filaments

BACKGROUND: PRPP synthase (PRPS) transfers the pyrophosphate groups from ATP to ribose-5-phosphate to produce 5-phosphate ribose-1-pyrophosphate (PRPP), a key intermediate in the biosynthesis of several metabolites including nucleotides, dinucleotides and some amino acids. There are three PRPS isofo...

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Detalles Bibliográficos
Autores principales:	Lu, Guang-Ming, Hu, Huan-Huan, Chang, Chia-Chun, Zhong, Jiale, Zhou, Xian, Guo, Chen-Jun, Zhang, Tianyi, Li, Yi-Lan, Yin, Boqi, Liu, Ji-Long
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227994/ https://www.ncbi.nlm.nih.gov/pubmed/37248548 http://dx.doi.org/10.1186/s13578-023-01037-z

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