DNA topoisomerase 1 represses HIV-1 promoter activity through its interaction with a guanine quadruplex present in the LTR sequence

BACKGROUND: Once integrated in the genome of infected cells, HIV-1 provirus is transcribed by the cellular transcription machinery. This process is regulated by both viral and cellular factors, which are necessary for an efficient viral replication as well as for the setting up of viral latency, lea...

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Detalles Bibliográficos
Autores principales: Lista, María José, Jousset, Anne-Caroline, Cheng, Mingpan, Saint-André, Violaine, Perrot, Elouan, Rodrigues, Melissa, Di Primo, Carmelo, Gadelle, Danielle, Toccafondi, Elenia, Segeral, Emmanuel, Berlioz-Torrent, Clarisse, Emiliani, Stéphane, Mergny, Jean-Louis, Lavigne, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228017/
https://www.ncbi.nlm.nih.gov/pubmed/37254203
http://dx.doi.org/10.1186/s12977-023-00625-8

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