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Akkermansia muciniphila, which is enriched in the gut microbiota by metformin, improves cognitive function in aged mice by reducing the proinflammatory cytokine interleukin-6

BACKGROUND: Metformin, a type 2 diabetes treatment, improves the cognitive function of aged mice; however, whether the protective effects of metformin on cognitive function in aged mice are associated with the gut microbiome is poorly understood. Although some studies suggest that the gut microbe co...

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Detalles Bibliográficos
Autores principales: Zhu, Xiaoqi, Shen, Junyan, Feng, Shengyu, Huang, Ce, Wang, Hao, Huo, Fengjiao, Liu, Hailiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228018/
https://www.ncbi.nlm.nih.gov/pubmed/37254162
http://dx.doi.org/10.1186/s40168-023-01567-1