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Recognition and management of hemorrhaging in combination with emerging enterogenic sepsis during a hepatectomy: a case report

BACKGROUND: Patients with hemorrhagic shock may develop emerging enterogenic sepsis due to damage to the intestinal mucosal barrier and translocation of intestinal bacteria and endotoxins caused by ischemic injury. Because of the dual effects of anesthesia state and hemorrhagic shock, perioperative...

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Autores principales: Chen, Yingjie, Liao, Yanling, Chen, Xiaoying, Fan, Hanliang, Lin, Daoyi, Zheng, Ting, Chen, Xiaohui, Gong, Cansheng, Gao, Fei, Jiang, Jundan, Zheng, Xiaochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228049/
https://www.ncbi.nlm.nih.gov/pubmed/37254051
http://dx.doi.org/10.1186/s12871-023-02108-x
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author Chen, Yingjie
Liao, Yanling
Chen, Xiaoying
Fan, Hanliang
Lin, Daoyi
Zheng, Ting
Chen, Xiaohui
Gong, Cansheng
Gao, Fei
Jiang, Jundan
Zheng, Xiaochun
author_facet Chen, Yingjie
Liao, Yanling
Chen, Xiaoying
Fan, Hanliang
Lin, Daoyi
Zheng, Ting
Chen, Xiaohui
Gong, Cansheng
Gao, Fei
Jiang, Jundan
Zheng, Xiaochun
author_sort Chen, Yingjie
collection PubMed
description BACKGROUND: Patients with hemorrhagic shock may develop emerging enterogenic sepsis due to damage to the intestinal mucosal barrier and translocation of intestinal bacteria and endotoxins caused by ischemic injury. Because of the dual effects of anesthesia state and hemorrhagic shock, perioperative emerging enterogenic sepsis is even more rare and insidious. CASE PRESENTATION: We reported a case of 56-year-old man who underwent right hepatectomy for intrahepatic bile duct stones. Severe hemorrhage occurred during the procedure and the hemodynamics neither improved nor worsened after rehydration therapy and vasoactive drug administration. Based on the patient’s history and clinical presentation, a possible enterogenic sepsis was considered. After anti-infective treatment and hormone supplementation, the patient’s circulation improved significantly and he had an uneventful recovery. CONCLUSION: The possibility of emerging enterogenic sepsis in hemorrhagic shock must always be taken into consideration. Familiarity with the risk factors and pathophysiological alterations of enterogenic sepsis is a prerequisite for early recognition and sound clinical decision making. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12871-023-02108-x.
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spelling pubmed-102280492023-05-31 Recognition and management of hemorrhaging in combination with emerging enterogenic sepsis during a hepatectomy: a case report Chen, Yingjie Liao, Yanling Chen, Xiaoying Fan, Hanliang Lin, Daoyi Zheng, Ting Chen, Xiaohui Gong, Cansheng Gao, Fei Jiang, Jundan Zheng, Xiaochun BMC Anesthesiol Case Report BACKGROUND: Patients with hemorrhagic shock may develop emerging enterogenic sepsis due to damage to the intestinal mucosal barrier and translocation of intestinal bacteria and endotoxins caused by ischemic injury. Because of the dual effects of anesthesia state and hemorrhagic shock, perioperative emerging enterogenic sepsis is even more rare and insidious. CASE PRESENTATION: We reported a case of 56-year-old man who underwent right hepatectomy for intrahepatic bile duct stones. Severe hemorrhage occurred during the procedure and the hemodynamics neither improved nor worsened after rehydration therapy and vasoactive drug administration. Based on the patient’s history and clinical presentation, a possible enterogenic sepsis was considered. After anti-infective treatment and hormone supplementation, the patient’s circulation improved significantly and he had an uneventful recovery. CONCLUSION: The possibility of emerging enterogenic sepsis in hemorrhagic shock must always be taken into consideration. Familiarity with the risk factors and pathophysiological alterations of enterogenic sepsis is a prerequisite for early recognition and sound clinical decision making. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12871-023-02108-x. BioMed Central 2023-05-30 /pmc/articles/PMC10228049/ /pubmed/37254051 http://dx.doi.org/10.1186/s12871-023-02108-x Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Chen, Yingjie
Liao, Yanling
Chen, Xiaoying
Fan, Hanliang
Lin, Daoyi
Zheng, Ting
Chen, Xiaohui
Gong, Cansheng
Gao, Fei
Jiang, Jundan
Zheng, Xiaochun
Recognition and management of hemorrhaging in combination with emerging enterogenic sepsis during a hepatectomy: a case report
title Recognition and management of hemorrhaging in combination with emerging enterogenic sepsis during a hepatectomy: a case report
title_full Recognition and management of hemorrhaging in combination with emerging enterogenic sepsis during a hepatectomy: a case report
title_fullStr Recognition and management of hemorrhaging in combination with emerging enterogenic sepsis during a hepatectomy: a case report
title_full_unstemmed Recognition and management of hemorrhaging in combination with emerging enterogenic sepsis during a hepatectomy: a case report
title_short Recognition and management of hemorrhaging in combination with emerging enterogenic sepsis during a hepatectomy: a case report
title_sort recognition and management of hemorrhaging in combination with emerging enterogenic sepsis during a hepatectomy: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228049/
https://www.ncbi.nlm.nih.gov/pubmed/37254051
http://dx.doi.org/10.1186/s12871-023-02108-x
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