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Is metabolism the magic bullet for targeted cancer therapy?

Altered cellular metabolism has long been recognized as a hallmark of cancer. Oncogenic signaling cascades induce metabolic rewiring that further supports tumorigenesis, therapy resistance and metastasis. In view of this, the Collection on ‘Cancer Metabolism’ highlights the current views and focus o...

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Detalles Bibliográficos
Autores principales: Trajkovic-Arsic, Marija, Subramani, Elavarasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228052/
https://www.ncbi.nlm.nih.gov/pubmed/37254076
http://dx.doi.org/10.1186/s12885-023-10999-9
Descripción
Sumario:Altered cellular metabolism has long been recognized as a hallmark of cancer. Oncogenic signaling cascades induce metabolic rewiring that further supports tumorigenesis, therapy resistance and metastasis. In view of this, the Collection on ‘Cancer Metabolism’ highlights the current views and focus of research on personalized medicine approach to target metabolism for cancer therapy.