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Severe metabolic acidosis due to massive metformin overdose in a man: a case report
Metformin-associated lactic acidosis is an extremely unusual but potentially life-threatening condition. This condition is typically observed in individuals who are suicidal or have type II diabetes mellitus (DM) and have taken an overdose of metformin. In this case, we present the instance of a 43-...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228116/ https://www.ncbi.nlm.nih.gov/pubmed/37260725 http://dx.doi.org/10.1093/omcr/omad049 |
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author | Manouchehri, Aliasghar Rashidian, Hale Zakariaei, Zakaria |
author_facet | Manouchehri, Aliasghar Rashidian, Hale Zakariaei, Zakaria |
author_sort | Manouchehri, Aliasghar |
collection | PubMed |
description | Metformin-associated lactic acidosis is an extremely unusual but potentially life-threatening condition. This condition is typically observed in individuals who are suicidal or have type II diabetes mellitus (DM) and have taken an overdose of metformin. In this case, we present the instance of a 43-year-old man who had type II DM and was addicted to oral opium. Following a suicide attempt with an overdose of metformin, he experienced symptoms such as nausea, vomiting, weakness and lactic acidosis. However, prompt and effective treatment was administered, including hemodialysis and adequate hemodynamic resuscitation, leading to a successful outcome. |
format | Online Article Text |
id | pubmed-10228116 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-102281162023-05-31 Severe metabolic acidosis due to massive metformin overdose in a man: a case report Manouchehri, Aliasghar Rashidian, Hale Zakariaei, Zakaria Oxf Med Case Reports Case Report Metformin-associated lactic acidosis is an extremely unusual but potentially life-threatening condition. This condition is typically observed in individuals who are suicidal or have type II diabetes mellitus (DM) and have taken an overdose of metformin. In this case, we present the instance of a 43-year-old man who had type II DM and was addicted to oral opium. Following a suicide attempt with an overdose of metformin, he experienced symptoms such as nausea, vomiting, weakness and lactic acidosis. However, prompt and effective treatment was administered, including hemodialysis and adequate hemodynamic resuscitation, leading to a successful outcome. Oxford University Press 2023-05-30 /pmc/articles/PMC10228116/ /pubmed/37260725 http://dx.doi.org/10.1093/omcr/omad049 Text en © The Author(s) 2023. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Case Report Manouchehri, Aliasghar Rashidian, Hale Zakariaei, Zakaria Severe metabolic acidosis due to massive metformin overdose in a man: a case report |
title | Severe metabolic acidosis due to massive metformin overdose in a man: a case report |
title_full | Severe metabolic acidosis due to massive metformin overdose in a man: a case report |
title_fullStr | Severe metabolic acidosis due to massive metformin overdose in a man: a case report |
title_full_unstemmed | Severe metabolic acidosis due to massive metformin overdose in a man: a case report |
title_short | Severe metabolic acidosis due to massive metformin overdose in a man: a case report |
title_sort | severe metabolic acidosis due to massive metformin overdose in a man: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228116/ https://www.ncbi.nlm.nih.gov/pubmed/37260725 http://dx.doi.org/10.1093/omcr/omad049 |
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