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Severe metabolic acidosis due to massive metformin overdose in a man: a case report

Metformin-associated lactic acidosis is an extremely unusual but potentially life-threatening condition. This condition is typically observed in individuals who are suicidal or have type II diabetes mellitus (DM) and have taken an overdose of metformin. In this case, we present the instance of a 43-...

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Autores principales: Manouchehri, Aliasghar, Rashidian, Hale, Zakariaei, Zakaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228116/
https://www.ncbi.nlm.nih.gov/pubmed/37260725
http://dx.doi.org/10.1093/omcr/omad049
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author Manouchehri, Aliasghar
Rashidian, Hale
Zakariaei, Zakaria
author_facet Manouchehri, Aliasghar
Rashidian, Hale
Zakariaei, Zakaria
author_sort Manouchehri, Aliasghar
collection PubMed
description Metformin-associated lactic acidosis is an extremely unusual but potentially life-threatening condition. This condition is typically observed in individuals who are suicidal or have type II diabetes mellitus (DM) and have taken an overdose of metformin. In this case, we present the instance of a 43-year-old man who had type II DM and was addicted to oral opium. Following a suicide attempt with an overdose of metformin, he experienced symptoms such as nausea, vomiting, weakness and lactic acidosis. However, prompt and effective treatment was administered, including hemodialysis and adequate hemodynamic resuscitation, leading to a successful outcome.
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spelling pubmed-102281162023-05-31 Severe metabolic acidosis due to massive metformin overdose in a man: a case report Manouchehri, Aliasghar Rashidian, Hale Zakariaei, Zakaria Oxf Med Case Reports Case Report Metformin-associated lactic acidosis is an extremely unusual but potentially life-threatening condition. This condition is typically observed in individuals who are suicidal or have type II diabetes mellitus (DM) and have taken an overdose of metformin. In this case, we present the instance of a 43-year-old man who had type II DM and was addicted to oral opium. Following a suicide attempt with an overdose of metformin, he experienced symptoms such as nausea, vomiting, weakness and lactic acidosis. However, prompt and effective treatment was administered, including hemodialysis and adequate hemodynamic resuscitation, leading to a successful outcome. Oxford University Press 2023-05-30 /pmc/articles/PMC10228116/ /pubmed/37260725 http://dx.doi.org/10.1093/omcr/omad049 Text en © The Author(s) 2023. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Manouchehri, Aliasghar
Rashidian, Hale
Zakariaei, Zakaria
Severe metabolic acidosis due to massive metformin overdose in a man: a case report
title Severe metabolic acidosis due to massive metformin overdose in a man: a case report
title_full Severe metabolic acidosis due to massive metformin overdose in a man: a case report
title_fullStr Severe metabolic acidosis due to massive metformin overdose in a man: a case report
title_full_unstemmed Severe metabolic acidosis due to massive metformin overdose in a man: a case report
title_short Severe metabolic acidosis due to massive metformin overdose in a man: a case report
title_sort severe metabolic acidosis due to massive metformin overdose in a man: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228116/
https://www.ncbi.nlm.nih.gov/pubmed/37260725
http://dx.doi.org/10.1093/omcr/omad049
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