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Recurrent gastrointestinal bleeding due to vascular malformations in a girl with Turner syndrome
Turner syndrome (TS) is a genetic defect accompanied by gonadal dysgenesis, short stature, characteristic dysmorphic features, congenital heart and kidneys defects, and other diseases. One of the less common are vascular malformations in the gastrointestinal (GI) tract. They are asymptomatic in some...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Termedia Publishing House
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228191/ https://www.ncbi.nlm.nih.gov/pubmed/34431260 http://dx.doi.org/10.5114/pedm.2021.105636 |
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author | Witkowska-Krawczak, Ewa Zapolska, Anna Banaszkiewicz, Aleksandra Kucharska, Anna |
author_facet | Witkowska-Krawczak, Ewa Zapolska, Anna Banaszkiewicz, Aleksandra Kucharska, Anna |
author_sort | Witkowska-Krawczak, Ewa |
collection | PubMed |
description | Turner syndrome (TS) is a genetic defect accompanied by gonadal dysgenesis, short stature, characteristic dysmorphic features, congenital heart and kidneys defects, and other diseases. One of the less common are vascular malformations in the gastrointestinal (GI) tract. They are asymptomatic in some patients, but can also cause GI bleeding. We present a description of a 12-year-old patient with TS and vascular malformations in the GI tract who was admitted to the hospital because of recurrent microcytic anemia. At the age of 15, she started estrogen therapy due to hypogonadism. Since then, the bleeding has stopped and the number of malformations on follow-up colonoscopy has been significantly decreased. In TS patients with iron deficiency anemia, the differential diagnostics should include vascular defects in the GI. There are evidences, that estrogen therapy may limit the number of lesions and reduce the risk of bleeding. |
format | Online Article Text |
id | pubmed-10228191 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Termedia Publishing House |
record_format | MEDLINE/PubMed |
spelling | pubmed-102281912023-06-05 Recurrent gastrointestinal bleeding due to vascular malformations in a girl with Turner syndrome Witkowska-Krawczak, Ewa Zapolska, Anna Banaszkiewicz, Aleksandra Kucharska, Anna Pediatr Endocrinol Diabetes Metab Case report | Opis przypadku Turner syndrome (TS) is a genetic defect accompanied by gonadal dysgenesis, short stature, characteristic dysmorphic features, congenital heart and kidneys defects, and other diseases. One of the less common are vascular malformations in the gastrointestinal (GI) tract. They are asymptomatic in some patients, but can also cause GI bleeding. We present a description of a 12-year-old patient with TS and vascular malformations in the GI tract who was admitted to the hospital because of recurrent microcytic anemia. At the age of 15, she started estrogen therapy due to hypogonadism. Since then, the bleeding has stopped and the number of malformations on follow-up colonoscopy has been significantly decreased. In TS patients with iron deficiency anemia, the differential diagnostics should include vascular defects in the GI. There are evidences, that estrogen therapy may limit the number of lesions and reduce the risk of bleeding. Termedia Publishing House 2021-09-30 2021-09 /pmc/articles/PMC10228191/ /pubmed/34431260 http://dx.doi.org/10.5114/pedm.2021.105636 Text en Copyright © Polish Society of Pediatric Endocrinology and Diabetes https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs (CC BY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) ), allowing third parties to download and share its works but not commercially purposes or to create derivative works. |
spellingShingle | Case report | Opis przypadku Witkowska-Krawczak, Ewa Zapolska, Anna Banaszkiewicz, Aleksandra Kucharska, Anna Recurrent gastrointestinal bleeding due to vascular malformations in a girl with Turner syndrome |
title | Recurrent gastrointestinal bleeding due to vascular malformations in a girl with Turner syndrome |
title_full | Recurrent gastrointestinal bleeding due to vascular malformations in a girl with Turner syndrome |
title_fullStr | Recurrent gastrointestinal bleeding due to vascular malformations in a girl with Turner syndrome |
title_full_unstemmed | Recurrent gastrointestinal bleeding due to vascular malformations in a girl with Turner syndrome |
title_short | Recurrent gastrointestinal bleeding due to vascular malformations in a girl with Turner syndrome |
title_sort | recurrent gastrointestinal bleeding due to vascular malformations in a girl with turner syndrome |
topic | Case report | Opis przypadku |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228191/ https://www.ncbi.nlm.nih.gov/pubmed/34431260 http://dx.doi.org/10.5114/pedm.2021.105636 |
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