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Astragaloside IV Attenuates High-Glucose-Induced Impairment in Diabetic Nephropathy by Increasing Klotho Expression via the NF-κB/NLRP3 Axis

OBJECTIVE: Deficiencies in klotho are implicated in various kidney dysfunctions including diabetic nephropathy (DN) related to inflammatory responses. Klotho is closely related to inflammatory responses and is a potential target for ameliorating kidney failure. Pyroptosis, an inflammatory form of pr...

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Detalles Bibliográficos
Autores principales:	He, Jiaxin, Cui, Jialin, Shi, Yimin, Wang, Tao, Xin, Junyan, Li, Yimeng, Shan, Xiaomeng, Zhu, Zhiyao, Gao, Yanbin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228232/ https://www.ncbi.nlm.nih.gov/pubmed/37261217 http://dx.doi.org/10.1155/2023/7423661

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