Sites of transcription initiation drive mRNA isoform selection

The generation of distinct messenger RNA isoforms through alternative RNA processing modulates the expression and function of genes, often in a cell-type-specific manner. Here, we assess the regulatory relationships between transcription initiation, alternative splicing, and 3′ end site selection. A...

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Detalles Bibliográficos
Autores principales: Alfonso-Gonzalez, Carlos, Legnini, Ivano, Holec, Sarah, Arrigoni, Laura, Ozbulut, Hasan Can, Mateos, Fernando, Koppstein, David, Rybak-Wolf, Agnieszka, Bönisch, Ulrike, Rajewsky, Nikolaus, Hilgers, Valérie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228280/
https://www.ncbi.nlm.nih.gov/pubmed/37178687
http://dx.doi.org/10.1016/j.cell.2023.04.012

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